Human noroviruses are recognised as the major global cause of viral gastroenteritis. Here,
we provide an overview of notable advances in norovirus research and provide a short …

Enteric viruses display intricate adaptations to the host mucosal immune system to
successfully reproduce in the gastrointestinal tract and cause maladies ranging from …

SARS-CoV-2 is the causative agent behind the COVID-19 pandemic, responsible for over
170 million infections, and over 3.7 million deaths worldwide. Efforts to test, treat and …

While knowledge of protein-protein interactions (PPIs) is critical for understanding virus-host
relationships, limitations on the scalability of high-throughput methods have hampered their …

Human norovirus is the primary cause of non-bacterial gastroenteritis globally and is the
second leading cause of diarrheal deaths in children in developing countries. However …

Interferon-lambda (IFN-λ) is a recently described cytokine found to be of critical importance
in innate immune regulation of intestinal viruses. Endogenous IFN-λ has potent antiviral …

Knowledge of the host factors required for norovirus replication has been hindered by the
challenges associated with culturing human noroviruses. We have combined proteomic …

Interferons (IFNs) are key host cytokines in the innate immune response to viral infection,
and recent work has identified unique roles for IFN subtypes in regulating different aspects …

Viral infections impose major stress on the host cell. In response, stress pathways can
rapidly deploy defence mechanisms by shutting off the protein synthesis machinery and …

The Caliciviridae are a family of viruses with a single-stranded, non-segmented RNA
genome of positive polarity. The ongoing discovery of caliciviruses has increased the …