Even though osteoarthritis (OA) is mainly considered as a degradative condition of the
articular cartilage, there is increasing body of data demonstrating the involvement of all …

Osteoarthritis (OA) is a major disabling disease and is ranked as a major cause of chronic
pain in adults. The pathology of the illness is characterized by a loss of articular cartilage …

Neuroinflammation is an important component of Alzheimer's disease (AD) pathogenesis
and has been implicated in neurodegeneration. Interleukin-1 (IL-1), a potent inflammatory …

Neuroinflammation is a conspicuous feature of Alzheimer disease (AD) pathology and is
thought to contribute to the ultimate neurodegeneration that ensues. IL-1β has emerged as a …

Neuroinflammatory conditions such as traumatic brain injury, aging, Alzheimer's disease,
and Down syndrome are often associated with cognitive dysfunction. Much research has …

The proinflammatory cytokine interleukin-1β (IL-1β) plays a significant role in leukocyte
recruitment to the CNS. Although acute effects of IL-1β signaling in the mouse brain have …

Temporomandibular joint osteoarthritis (TMJOA) is a common degenerative joint disease
that can cause severe pain and dysfunction. It has a serious impact on the quality of lives of …

Glial activation and neuroinflammation occur in neurodegenerative disease and brain injury,
however their presence in normal brain aging suggests that chronic neuroinflammation may …

PURPOSE: When osseous mandibular condylar resorption occurs there can be many
different diagnoses: inflammatory arthritis, TMJ compression, trauma, hormone imbalances …

The temporomandibular joint (TMJ) undergoes degenerative changes among patients who
suffer from arthritis, and yet the pathogenesis of TMJ osteoarthritis and rheumatoid arthritis is …