Recent developments in recombinant protein–based dengue vaccines
NK Tripathi, A Shrivastava - Frontiers in immunology, 2018 - frontiersin.org
Recombinant proteins are gaining enormous importance these days due to their wide
application as biopharmaceutical products and proven safety record. Various recombinant …
application as biopharmaceutical products and proven safety record. Various recombinant …
Structure and function of capsid protein in flavivirus infection and its applications in the development of vaccines and therapeutics
X Zhang, Y Zhang, R Jia, M Wang, Z Yin, A Cheng - Veterinary research, 2021 - Springer
Flaviviruses are enveloped single positive-stranded RNA viruses. The capsid (C), a
structural protein of flavivirus, is dimeric and alpha-helical, with several special structural …
structural protein of flavivirus, is dimeric and alpha-helical, with several special structural …
Antibody-dependent enhancement of viral infections
R Kulkarni - Dynamics of immune activation in viral diseases, 2020 - Springer
Antiviral antibodies constitute an important component of the host immune response against
viral infections and serve to neutralize and reduce infectivity of the virus. However, these …
viral infections and serve to neutralize and reduce infectivity of the virus. However, these …
Dengue viruses and promising envelope protein domain III-based vaccines
H Fahimi, M Mohammadipour… - Applied microbiology …, 2018 - Springer
Dengue viruses are emerging mosquito-borne pathogens belonging to Flaviviridae family
which are transmitted to humans via the bites of infected mosquitoes Aedes aegypti and …
which are transmitted to humans via the bites of infected mosquitoes Aedes aegypti and …
Anti-Flavivirus Vaccines: Review of the Present Situation and Perspectives of Subunit Vaccines Produced in Escherichia coli
This article aims to review the present status of anti-flavivirus subunit vaccines, both those at
the experimental stage and those already available for clinical use. Aspects regarding …
the experimental stage and those already available for clinical use. Aspects regarding …
Can complementary prime-boost immunization strategies be an alternative and promising vaccine approach against dengue virus?
Dengue is one of the most important diseases transmitted by mosquitoes. Dengvaxia®, a
vaccine registered in several countries, cannot be administered to non-immune individuals …
vaccine registered in several countries, cannot be administered to non-immune individuals …
[HTML][HTML] Dengue and Zika virus domain III-flagellin fusion and glycan-masking E antigen for prime-boost immunization
The viral E proteins of dengue virus (DENV) and Zika virus (ZIKV) are the major viral
proteins involved in receptor binding and fusion, and for the induction of protective …
proteins involved in receptor binding and fusion, and for the induction of protective …
Addition of nucleotide adjuvants enhances the immunogenicity of a recombinant subunit vaccine against the Zika virus in BALB/c mice
Zika virus (ZIKV) infection remains a global public health problem. After the “Public Health
Emergencies of International Concern” declared in February 2016, the incidence of new …
Emergencies of International Concern” declared in February 2016, the incidence of new …
Recombinant protein based on domain III and capsid regions of zika virus induces humoral and cellular immune response in immunocompetent BALB/c mice
Zika virus infection continues to be a global concern for human health due to the high-risk
association of the disease with neurological disorders and microcephaly in newborn …
association of the disease with neurological disorders and microcephaly in newborn …
Aiming at the heart: the capsid protein of dengue virus as a vaccine candidate
Introduction: Dengue fever remains as a health problem worldwide. Although Dengvaxia®,
was registered in several countries, the results after the immunization of people suggest an …
was registered in several countries, the results after the immunization of people suggest an …