The regulatory role of the immune system in maintaining bone homeostasis and restoring its
functionality, when disturbed due to trauma or injury, has become evident in recent years …

Bone defects are a common disease threatening the health of many people. Calcium
phosphate (CaP) is an ideal bone substitutive material that is widely used for bone repair …

The insufficient osteogenesis and osseointegration of porous titanium based scaffold limit its
further application. Early angiogenesis is important for scaffold survival. It is necessary to …

Biomaterial implantation triggers inflammatory reactions. Understanding the effect of
physicochemical features of biomaterials on the release of inflammatory cytokines from …

Immune cells are sensitive to the microstructural and textural properties of materials. Tuning
the structural features of synthetic bone grafts could be a valuable strategy to regulate the …

Bone cements can be defined as biomaterials obtained by mixing a powder phase and a
liquid phase, which can be molded and implanted as a paste and can set once implanted …

With the increasing demand for low-cost and more efficient dental implants, there is an
urgent need to develop new manufacturing approaches and implants with better …

Macrophages and osteoclasts are both derived from monocyte/macrophage lineage, which
plays as the osteoclastic part of bone metabolism. Although they are regulated by bone …

Regenerative bone implants promote new bone formation and ideally degrade
simultaneously to osteogenesis. Although clinically established calcium phosphate bone …

Human mesenchymal stromal cells (hMSCs) seeded on calcium phosphate (CaP)
bioceramics are extensively explored in bone tissue engineering and have recently shown …