The value of pyrans as anticancer scaffolds in medicinal chemistry

D Kumar, P Sharma, H Singh, K Nepali, GK Gupta… - RSC …, 2017 - pubs.rsc.org
Pyran is an oxygen-containing heterocyclic moiety, which exhibits an array of
pharmacological properties. Pyran is also one of the important structural subunits found …

New mixed ligand copper (II) hydrazone‐based complexes: Synthesis, characterization, crystal structure, DNA/RNA/BSA binding, in vitro anticancer, apoptotic activity …

SA Elsayed, IM Elnabky, A di Biase… - Applied …, 2022 - Wiley Online Library
Four new mixed ligand copper (II) complexes with the general formula [Cu (L)(B)] n (1)–
(4)(H2L= dehydroacetic acid benzoyl hydrazone Schiff base, B= H2O (1), DMSO (2) …

Dehydroacetic acid a privileged medicinal scaffold: A concise review

A Grover, A Kumar, RK Tittal, K Lal - Archiv der Pharmazie, 2024 - Wiley Online Library
From the last decade, research on dehydroacetic acid (DHA) and its derivatives has
increased immensely due to its significant role in various fields, including medicine …

Synthesis, characterization, and pharmacological evaluation of selected aromatic amines

H Ismail, B Mirza, I Haq, M Shabbir, Z Akhter… - Journal of …, 2015 - Wiley Online Library
Aromatic amines 1‐amino‐4‐phenoxybenzene (A‐1A), 2‐(4‐aminophenoxy) naphthalene
(A‐2A), and 1‐(4‐aminophenoxy) naphthalene (A‐3A) were synthesized by the reduction of …

Synthesis and antibacterial activities of enamine derivatives of dehydroacetic acid

AG Baldwin, J Bevan, D Brough, R Ledder… - Medicinal Chemistry …, 2018 - Springer
Dehydroacetic acid is a common pyrone derivative used commercially as an antibacterial
and antifungal agent. Based on the synthesis of dehydroacetic acid (1) from N …

Ruthenium (II) complexes containing dehydroacetic acid and its imine derivative ligands. Synthesis, characterization and cancer cell growth anti-proliferation activity …

KH Chen, TH Lin, TE Hsu, YJ Li, GH Chen… - Journal of …, 2018 - Elsevier
Two dehydroacetic acid (DHA, L 1 H) related imine ligands, L 2 H and L 3 H were obtained
in moderate yields by reacting DHA with 2, 4, 6-trimethylaniline and phenylhydrazine …

Dehydroacetic acid (part 1): chemical and pharmacological properties

AE Jilalat - Moroccan Journal of Heterocyclic Chemistry, 2017 - revues.imist.ma
Dehydracetic acid and its derivatives are widely used as an intermediates in organic
synthesis. In this paper, we report several methods used for synthesizing this acid. We will …

Synthesis, characterization, electrochemical and biological activity studies of tetradentate Schiff base and its Mn (IV) complexes

D Basumatary, P Mahanta, C Medhi… - Journal of the Iranian …, 2024 - Springer
Disalicylaldehyde fumaroyldihydrazone (slfhH4) interacts with Mn (OAc) 2· 4H2O in
presence of KOH in the methanolic medium giving [MnIV (slfh)(A) 2]· 2H2O and [MnIV …

Selective Complexation of Hydrazone Based Ketimine with 3d, 4d, and 5d Metals: Synthesis, Characterization, and Biological Activity

F Ahmad, MB Taj, SA Tirmizi, W Alelwani… - Russian Journal of …, 2019 - Springer
The hydrazone derived ketimine of dehydroacetic acid and its metal {Cu (II), Ni (II), Zn (II), Fe
(III), Cd (II), Pd (II), La (III), Nd (III), Ce (III)} complexes are synthesized and characterized by …

Crystal structure, Hirshfeld surface and reactivity of novel ligand-LAT1 derived from dehydroacetic acid: intermolecular interactions with SARS-Cov-2/main protease

I Denni, C Ait Ramdane-Terbouche… - … Crystals and Liquid …, 2021 - Taylor & Francis
The crystals of new ligand, namely (3 E)-6-methyl-3-{1-[(pyridin-3-ylmethyl) amino] ethylene}-
2 H-pyran-2, 4 (3 H)-dione)(LAT1), were synthesized using the evaporation solution …