Modeling tracer kinetics in dynamic Gd‐DTPA MR imaging

PS Tofts - Journal of magnetic resonance imaging, 1997 - Wiley Online Library
Three major models (from Tofts, Larsson, and Brix) for collecting and analyzing dynamic MRI
gadolinium‐diethylenetriamine penta‐acetic acid (Gd‐DTPA) data are examined. All models …

Dynamic contrast‐enhanced MRI in clinical oncology: current status and future directions

AR Padhani - Journal of Magnetic Resonance Imaging: An …, 2002 - Wiley Online Library
Dynamic contrast‐enhanced magnetic resonance imaging (DCE‐MRI) is performed after the
administration of intravenous contrast medium to noninvasively access tumor vascular …

Quantitative diffusion imaging in breast cancer: a clinical prospective study

E Rubesova, AS Grell, V De Maertelaer… - Journal of Magnetic …, 2006 - Wiley Online Library
Purpose To study the correlation between apparent diffusion coefficient (ADC) and
pathology in patients with undefined breast lesion, to validate how accurately ADC is related …

Combretastatin A4 phosphate has tumor antivascular activity in rat and man as demonstrated by dynamic magnetic resonance imaging

SM Galbraith, RJ Maxwell, MA Lodge… - Journal of clinical …, 2003 - ascopubs.org
Purpose: Combretastatin A4 phosphate (CA4P) is a novel vascular targeting agent. Dynamic
contrast enhanced magnetic resonance imaging (DCE-MRI) studies were performed to …

Magnetic resonance imaging—monitored acute blood-brain barrier changes in experimental traumatic brain injury

P Barzó, A Marmarou, P Fatouros, F Corwin… - Journal of …, 1996 - thejns.org
✓ The authors posit that cellular edema is the major contributor to brain swelling in diffuse
head injury and that the contribution of vasogenic edema may be overemphasized. The …

Engineering the tissue which encapsulates subcutaneous implants. II. Plasma–tissue exchange properties

AA Sharkawy, B Klitzman, GA Truskey… - Journal of Biomedical …, 1998 - Wiley Online Library
This study assesses the plasma–tissue exchange characteristics of the capsular tissue that
forms around implants and how they are affected by implant porosity. The number of vessels …

Effect of Vascular Targeting Agent in Rat Tumor Model: Dynamic Contrast-enhanced versus Diffusion-weighted MR Imaging1

HC Thoeny, F De Keyzer, V Vandecaveye, F Chen… - Radiology, 2005 - pubs.rsna.org
PURPOSE: To compare dynamic contrast material–enhanced magnetic resonance (MR)
imaging and diffusion-weighted MR imaging for noninvasive evaluation of early and late …

Correlation of dynamic contrast enhancement MRI parameters with microvessel density and VEGF for assessment of angiogenesis in breast cancer

MY Su, YC Cheung, JP Fruehauf, H Yu… - Journal of Magnetic …, 2003 - Wiley Online Library
Purpose To investigate the association between parameters obtained from dynamic contrast
enhanced MRI (DCE‐MRI) of breast cancer using different analysis approaches, as well as …

Method for quantitative mapping of dynamic MRI contrast agent uptake in human tumors

M Rijpkema, JHAM Kaanders… - Journal of Magnetic …, 2001 - Wiley Online Library
A method is presented for the acquisition and analysis of dynamic contrast‐enhanced (DCE)
MRI data, focused on the characterization of tumors in humans. Gadolinium (Gd) contrast …

Patlak plots of Gd‐DTPA MRI data yield blood–brain transfer constants concordant with those of 14C‐sucrose in areas of blood–brain opening

JR Ewing, RA Knight, TN Nagaraja… - … in Medicine: An …, 2003 - Wiley Online Library
The blood‐to‐brain transfer rate constant (Ki) of Gd‐DTPA was determined in MRI studies of
a rat model of transient cerebral ischemia. The longitudinal relaxation rate, R1, was …