A network-based neurobiological model of PTSD: evidence from structural and functional neuroimaging studies
Abstract Purpose of Review Although a fine-grained understanding of the neurobiology of
posttraumatic stress disorder (PTSD) is yet to be elucidated, the last two decades have seen …
posttraumatic stress disorder (PTSD) is yet to be elucidated, the last two decades have seen …
Chronic pain and chronic stress: two sides of the same coin?
CG Abdallah, P Geha - Chronic Stress, 2017 - journals.sagepub.com
Pain and stress share significant conceptual and physiological overlaps. Both phenomena
challenge the body's homeostasis and necessitate decision-making to help animals adapt to …
challenge the body's homeostasis and necessitate decision-making to help animals adapt to …
The neurobiology of depression, ketamine and rapid-acting antidepressants: Is it glutamate inhibition or activation?
The discovery of the antidepressant effects of ketamine has opened a breakthrough
opportunity to develop a truly novel class of safe, effective, and rapid-acting antidepressants …
opportunity to develop a truly novel class of safe, effective, and rapid-acting antidepressants …
Fear extinction relies on ventral hippocampal safety codes shaped by the amygdala
R Nguyen, K Koukoutselos, T Forro, S Ciocchi - Science Advances, 2023 - science.org
Extinction memory retrieval is influenced by spatial contextual information that determines
responding to conditioned stimuli (CS). However, it is poorly understood whether contextual …
responding to conditioned stimuli (CS). However, it is poorly understood whether contextual …
The neurobiology and pharmacotherapy of posttraumatic stress disorder
New approaches to the neurobiology of posttraumatic stress disorder (PTSD) are needed to
address the reported crisis in PTSD drug development. These new approaches may require …
address the reported crisis in PTSD drug development. These new approaches may require …
Default mode network abnormalities in posttraumatic stress disorder: A novel network-restricted topology approach
Disruption in the default mode network (DMN) has been implicated in numerous
neuropsychiatric disorders, including posttraumatic stress disorder (PTSD). However …
neuropsychiatric disorders, including posttraumatic stress disorder (PTSD). However …
Synaptic loss and the pathophysiology of PTSD: implications for ketamine as a prototype novel therapeutic
Abstract Purpose of Review Studies of the neurobiology and treatment of PTSD have
highlighted many aspects of the pathophysiology of this disorder that might be relevant to …
highlighted many aspects of the pathophysiology of this disorder that might be relevant to …
[HTML][HTML] A novel arousal-based individual screening reveals susceptibility and resilience to PTSD-like phenotypes in mice
Translational animal models for studying post-traumatic stress disorder (PTSD) are valuable
for elucidating the poorly understood neurobiology of this neuropsychiatric disorder. These …
for elucidating the poorly understood neurobiology of this neuropsychiatric disorder. These …
Prefrontal connectivity and glutamate transmission: relevance to depression pathophysiology and ketamine treatment
Background Prefrontal global brain connectivity with global signal regression (GBCr) was
proposed as a robust biomarker of depression and was associated with ketamine's …
proposed as a robust biomarker of depression and was associated with ketamine's …
Cerebellar and prefrontal cortical alterations in PTSD: structural and functional evidence
SE Holmes, D Scheinost, N DellaGioia… - Chronic …, 2018 - journals.sagepub.com
Background Neuroimaging studies have revealed that disturbances in network organization
of key brain regions may underlie cognitive and emotional dysfunction in posttraumatic …
of key brain regions may underlie cognitive and emotional dysfunction in posttraumatic …