The growing development of DNA nanostructures for potential healthcare‐related applications

D Mathur, IL Medintz - Advanced Healthcare Materials, 2019 - Wiley Online Library
DNA self‐assembly has proven to be a highly versatile tool for engineering complex and
dynamic biocompatible nanostructures from the bottom up with a wide range of potential …

Toward a more complete understanding of noncovalent interactions involving aromatic rings

SE Wheeler, JWG Bloom - The journal of physical chemistry A, 2014 - ACS Publications
Noncovalent interactions involving aromatic rings, which include π-stacking interactions,
anion-π interactions, and XH− π interactions, among others, are ubiquitous in chemical and …

An electrochemical aptasensor for multiplex antibiotics detection based on metal ions doped nanoscale MOFs as signal tracers and RecJf exonuclease-assisted …

M Chen, N Gan, Y Zhou, T Li, Q Xu, Y Cao, Y Chen - Talanta, 2016 - Elsevier
An ultrasensitive electrochemical aptasensor for simultaneous detection of oxytetracycline
(OTC) and kanamycin (KAN) has been developed based on metal ions doped metal organic …

Transposon DNA sequences facilitate the tissue-specific gene transfer of circulating tumor DNA between human cells

M Cinar, L Martinez-Medina, PK Puvvula… - Nucleic Acids …, 2024 - academic.oup.com
The exchange of genes between cells is known to play an important physiological and
pathological role in many organisms. We show that circulating tumor DNA (ctDNA) facilitates …

Quantifying the π-stacking interactions in nitroarene binding sites of proteins

Y An, JWG Bloom, SE Wheeler - The Journal of Physical …, 2015 - ACS Publications
Stacking interactions in nitroarene binding sites of proteins were studied through analyses of
structures in the protein data bank (PDB), as well as DFT and ab initio computations applied …

Contribution of phenylalanine side chain intercalation to the TATA-box binding protein–DNA interaction: molecular dynamics and dispersion-corrected density …

M Mondal, S Mukherjee, D Bhattacharyya - Journal of molecular modeling, 2014 - Springer
Deformation of DNA takes place quite often due to binding of small molecules or proteins
with DNA. Such deformation is significant due to minor groove binding and, besides …

Complexes of DNA with fluorescent dyes are effective reagents for detection of autoimmune antibodies

I Domljanovic, A Carstens, A Okholm, J Kjems… - Scientific Reports, 2017 - nature.com
To date, there are multiple assays developed that detect and quantify antibodies in biofluids.
Nevertheless, there is still a lack of simple approaches that specifically detect autoimmune …

Autoantibody profiling in lupus patients using synthetic nucleic acids

M Klecka, C Thybo, C Macaubas, I Solov'yov… - Scientific Reports, 2018 - nature.com
Autoantibodies to nuclear components of cells (antinuclear antibodies, ANA), including DNA
(a-DNA), are widely used in the diagnosis and subtyping of certain autoimmune diseases …

Retrotransposons facilitate the tissue-specific horizontal transfer of circulating tumor DNA between human cells

M Cinar, L Martinez-Medina, PK Puvvula, A Arakelyan… - bioRxiv, 2022 - biorxiv.org
A variety of organisms have been shown to have altered physiology or developed pathology
due to gene transfer, but mammals have never been shown to do so. Here, we show that …

Synthetic oligonucleotide antigens modified with locked nucleic acids detect disease specific antibodies

SV Samuelsen, IA Solov'yov, IM Balboni, E Mellins… - Scientific Reports, 2016 - nature.com
New techniques to detect and quantify antibodies to nucleic acids would provide a
significant advance over current methods, which often lack specificity. We investigate the …