Background Poultry bacterial pathogens are mainly controlled by using high-cost sanitary
measures and medical treatment. However, the drug-resistant strains of pathogens …

Avian Pathogenic Escherichia coli (APEC) is an extraintestinal pathotype of E. coli that leads
to a range of clinical manifestations, including respiratory, systemic and reproductive …

Escherichia coli strains that cause disease outside the intestine are known as extraintestinal
pathogenic E. coli (ExPEC) and include human uropathogenic E. coli (UPEC) and avian …

SUMMARY A candidate live vaccine for avian pathogenic Escherichia coli (APEC) was
constructed from a virulent field APEC O78 strain by mutation of the aroA gene. The mutant …

This study determined optimal conditions for experimental reproduction of colibacillosis by
aerosol administration of avian pathogenic Escherichia coli to 2-to-4-wk-old broiler chickens …

Abstract The Δ galE, Δ purA, and Δ aroA derivatives of avian septicemic Escherichia coli
EC99 strain (O78 serogroup) were constructed with a suicide vector containing the pir …

Attenuated derivatives (Δ cya Δ crp mutants) of an O2 and an O78 avian septicemic
Escherichia coli strain were used to immunize broiler chickens by spray to determine the …

Vaccination against bacteria offers its share of challenges, and important progress has been
made in recent years. Conventional vaccinology has protected poultry for decades with …

The immune response to four cell surface antigens of avian pathogenic Escherichia coli
(APEC) was investigated as the first step in identifying vaccine candidates. F1 pilus adhesin …

US8133493B2 - Regulated attenuation of live vaccines to enhance cross-protective
immunogenicity - Google Patents US8133493B2 - Regulated attenuation of live vaccines to …