Environmental mechanisms of orofacial clefts

MA Garland, K Reynolds, CJ Zhou - Birth defects research, 2020 - Wiley Online Library
Orofacial clefts (OFCs) are among the most common birth defects and impart a significant
burden on afflicted individuals and their families. It is increasingly understood that many …

Risk factors involved in orofacial cleft predisposition–review

A Kawalec, K Nelke, K Pawlas, H Gerber - Open Medicine, 2015 - degruyter.com
Clefts that occur in children are a special topic. Avoiding risk factors, and also an early
diagnosis of cleft possibility can result in minimizing or avoiding them. If on the other hand …

[PDF][PDF] Family history and risk factors for cleft lip and palate patients and their associated anomalies

A Jamilian, F Sarkarat, M Jafari, M Neshandar… - …, 2017 - researchgate.net
Background and aims. Several environmental and genetic issues have been suspected as
risk factors for oral clefts; and many studies have been conducted in this regard; however …

Differential methylation is associated with non-syndromic cleft lip and palate and contributes to penetrance effects

L Alvizi, X Ke, LA Brito, R Seselgyte, GE Moore… - Scientific reports, 2017 - nature.com
Non-syndromic cleft lip and/or palate (NSCLP) is a common congenital malformation with a
multifactorial model of inheritance. Although several at-risk alleles have been identified, they …

Parental risk factors for oral clefts among Central Africans, Southeast Asians, and Central Americans

JC Figueiredo, S Ly, KS Magee… - … Research Part A …, 2015 - Wiley Online Library
Background Several lifestyle and environmental exposures have been suspected as risk
factors for oral clefts, although few have been convincingly demonstrated. Studies across …

Dental caries and associated factors in 3 to 5-year-old children in Zhejiang Province, China: an epidemiological survey

N Zhou, H Zhu, Y Chen, W Jiang, X Lin, Y Tu, D Chen… - BMC oral health, 2019 - Springer
Background Dental caries in preschool children is prevalent worldwide, but data regarding
its magnitude and associated factors were not available for preschool children in Zhejiang …

[HTML][HTML] Influence of parental exposure to risk factors in the occurrence of oral clefts

SR Altoé, ÁH Borges, ATSC Neves… - Journal of …, 2020 - ncbi.nlm.nih.gov
Purpose: To analyze the influence of parental exposure to risk factors on the occurrence of
oral clefts. Materials and Method: A case-control study was conducted with 150 mothers of …

Environmental risk factors for nonsyndromic cleft lip and/or cleft palate in Xinjiang Province, China: A multiethnic study

Y Hong, X Xu, F Lian, R Chen - The Cleft Palate-Craniofacial …, 2021 - journals.sagepub.com
Objective: To determine the risk factors of the occurrence of nonsyndromic cleft lip and/or
cleft palate (NSCL/P) in Xinjiang Province, China. Design: The study included 359 patients …

Proportion of orofacial clefts attributable to recognized risk factors

JR Raut, RM Simeone, SC Tinker… - The Cleft Palate …, 2019 - journals.sagepub.com
Objective: Estimate the population attributable fraction (PAF) for a set of recognized risk
factors for orofacial clefts. Design: We used data from the National Birth Defects Prevention …

The role of smoke from cooking indoors over an open flame and parental smoking on the risk of cleft lip and palate: A case-control study in 7 low-resource countries

A Auslander, R McKean-Cowdin… - Journal of global …, 2020 - pmc.ncbi.nlm.nih.gov
Background Cleft is one of the most common birth defects globally and the lack of access to
surgery means millions are living untreated. Smoke exposure from cooking occurs …