[PDF][PDF] Failure to reconstitute CD4+ T-cells despite suppression of HIV replication under HAART

F Aiuti, I Mezzaroma - Aids Rev, 2006 - researchgate.net
HAART in HIV-1-infected individuals has a broad spectrum of clinical outcomes. In the
majority of patients, plasma viral load becomes undetectable and CD4+ T-cells increase …

CD4+ Cell Count 6 Years after Commencement of Highly Active Antiretroviral Therapy in Persons with Sustained Virologic Suppression

RD Moore, JC Keruly - Clinical infectious diseases, 2007 - academic.oup.com
Background. Sustained suppression of the human immunodeficiency virus (HIV) type 1 RNA
load with the use of highly active antiretroviral therapy (HAART) results in immunologic …

Enhanced T cell recovery in HIV-1–infected adults through IL-7 treatment

Y Levy, C Lacabaratz, L Weiss, JP Viard… - The Journal of …, 2009 - Am Soc Clin Investig
HIV infection results in CD4+ T cell deficiency, but efficient combination antiretroviral therapy
(c-ART) restores T cells and decreases morbidity and mortality. However, immune …

HIV RNA suppression and immune restoration: can we do better?

MR Pinzone, M Di Rosa, B Cacopardo… - Journal of …, 2012 - Wiley Online Library
HAART has significantly changed the natural history of HIV infection: patients receiving
antiretrovirals are usually able to control viremia, even though not all virological responders …

Viability and effectiveness of large-scale HIV treatment initiatives in sub-Saharan Africa: experience from western Kenya

K Wools-Kaloustian, S Kimaiyo, L Diero, A Siika… - Aids, 2006 - journals.lww.com
Objectives: To determine the clinical and immunological outcomes of a cohort of HIV-
infected patients receiving antiretroviral therapy. Design: Retrospective study of …

CD4 cell counts of 800 cells/mm3 or greater after 7 years of highly active antiretroviral therapy are feasible in most patients starting with 350 cells/mm3 or greater

L Gras, AM Kesselring, JT Griffin… - JAIDS Journal of …, 2007 - journals.lww.com
Objective: CD4 cell count changes in therapy-naive patients were investigated during 7
years of highly active antiretroviral therapy (HAART) in an observational cohort. Methods …

Long-term immunologic response to antiretroviral therapy in low-income countries: a collaborative analysis of prospective studies

D Nash, M Katyal, MWG Brinkhof, O Keiser, M May… - Aids, 2008 - journals.lww.com
Background: Few data are available on the long-term immunologic response to antiretroviral
therapy (ART) in resource-limited settings, where ART is being rapidly scaled up using a …

Older age and the response to and tolerability of antiretroviral therapy

MJ Silverberg, W Leyden, MA Horberg… - Archives of internal …, 2007 - jamanetwork.com
Background The unique health needs of a growing older adult population infected with
human immunodeficiency virus (HIV) require study, especially in terms of the response to …

Virological and immunological failure of HAART and associated risk factors among adults and adolescents in the Tigray region of Northern Ethiopia

GG Hailu, DG Hagos, AK Hagos, AG Wasihun… - PloS one, 2018 - journals.plos.org
Background Human immunodeficiency virus/Acquired immunodeficiency syndrome
associated morbidity and mortality has reduced significantly since the introduction of highly …

Poor initial CD4+ recovery with antiretroviral therapy prolongs immune depletion and increases risk for AIDS and non-AIDS diseases

JV Baker, G Peng, J Rapkin, D Krason… - JAIDS Journal of …, 2008 - journals.lww.com
Background: Low CD4+ increases risk for both AIDS-and non-AIDS-related morbidity and
mortality. The magnitude of CD4+ recovery early after initial antiretroviral therapy (ART) is …