Platelet-rich plasma: a comparative and economical therapy for wound healing and tissue regeneration

R Verma, S Kumar, P Garg, YK Verma - Cell and Tissue Banking, 2023 - Springer
Rise in the incidences of chronic degenerative diseases with aging makes wound care a
socio-economic burden and unceasingly necessitates a novel, economical, and efficient …

Constructing a cell microenvironment with biomaterial scaffolds for stem cell therapy

X Zhao, Q Li, Z Guo, Z Li - Stem cell research & therapy, 2021 - Springer
Stem cell therapy is widely recognized as a promising strategy for exerting therapeutic
effects after injury in degenerative diseases. However, limitations such as low cell retention …

Platelets facilitate the wound-healing capability of mesenchymal stem cells by mitochondrial transfer and metabolic reprogramming

J Levoux, A Prola, P Lafuste, M Gervais, N Chevallier… - Cell metabolism, 2021 - cell.com
Platelets are known to enhance the wound-healing activity of mesenchymal stem cells
(MSCs). However, the mechanism by which platelets improve the therapeutic potential of …

[PDF][PDF] The PI3k/Akt pathway is associated with angiogenesis, oxidative stress and survival of mesenchymal stem cells in pathophysiologic condition in ischemia

A Samakova, A Gazova, N Sabova, S Valaskova… - Physiol Res, 2019 - academia.edu
Ischemic diseases are characterized by reduced blood supply to a tissue or an organ due to
obstruction of blood vessels. The most serious and most common ischemic diseases include …

Bone marrow mesenchymal stem cell-derived exosomes carrying long noncoding RNA ZFAS1 alleviate oxidative stress and inflammation in ischemic stroke by …

H Yang, J Chen - Metabolic brain disease, 2022 - Springer
Background/aim Bone marrow mesenchymal stem cell (BMSC)-derived exosomes can
prevent oxidative stress and inflammation in cerebral ischemia-reperfusion injury. This study …

Mesenchymal stem cell therapy for ischemic stroke: a look into treatment mechanism and therapeutic potential

J Li, Q Zhang, W Wang, F Lin, S Wang, J Zhao - Journal of neurology, 2021 - Springer
Stroke, a global disease with a high disability rate, has limited options for functional
rehabilitation and results in an adverse impact on patients' lives. In recent years …

Magnetic particle targeting for diagnosis and therapy of lung cancers

M Saadat, MKD Manshadi, M Mohammadi… - Journal of Controlled …, 2020 - Elsevier
Over the past decade, the growing interest in targeted lung cancer therapy has guided
researchers toward the cutting edge of controlled drug delivery, particularly magnetic …

Mesenchymal stem cells for critical limb ischemia: their function, mechanism, and therapeutic potential

LV Lozano Navarro, X Chen… - Stem cell research & …, 2022 - Springer
Peripheral arterial disease is atherosclerotic occlusive disease of the lower extremity
arteries and afflicts hundreds of millions of individuals worldwide. Its most severe …

Emerging roles of mesenchymal stem cell therapy in patients with critical limb ischemia

Z Shirbaghaee, M Hassani, S Heidari Keshel… - Stem Cell Research & …, 2022 - Springer
Critical limb ischemia (CLI), the terminal stage of peripheral arterial disease (PAD), is
characterized by an extremely high risk of amputation and vascular issues, resulting in …

Mesenchymal stem/stromal cell therapy in blood–brain barrier preservation following ischemia: Molecular mechanisms and prospects

PT Do, CC Wu, YH Chiang, CJ Hu… - International journal of …, 2021 - mdpi.com
Ischemic stroke is the leading cause of mortality and long-term disability worldwide.
Disruption of the blood–brain barrier (BBB) is a prominent pathophysiological mechanism …