This review summarises known sesquiterpenes whose biosyntheses proceed through the
intermediate germacrene A. First, the occurrence and biosynthesis of germacrene A in …

Great efforts have been directed toward alkene π bond amination. In contrast, analogous
functionalization of the adjacent C (sp3)–C (sp2) σ bonds is much rarer. Here we report how …

Chemical synthesis typically relies on reactions that generate complexity through
elaboration of simple starting materials. Less common are deconstructive strategies toward …

Fifteen previously undescribed sesquiterpenoids (pogocablenes AO), three first discovered
natural patchoulol-type ones, coupled with fourteen known ones, were isolated from the …

Although bicyclic acids have been reported to be the major naphthenic acids in oil sands
process-affected water (OSPW) and a well-accepted screening assay indicated that some …

Purpose The aim of this study was to evaluate the effect of Pogostemon cablin essential oil
(PEO) on leukocyte behavior in the inflammatory response. Methods and results PEO was …

This review highlights the history and recent advances in dealkenylative functionalization.
Through this deconstructive strategy, radical functionalizations occur under mild, robust …

A facile two-step synthetic route for preparing the novel tetracyclic skeleton of benzofused 2,
6-diaryl-1-azahomoisotwistanes 2 had been developed. The route was carried out by a one …

A synthesis of the tricyclic partly substituted core structure of palhinine A was achieved. To
reach the bicyclo [2.2. 2] octane motif a domino Michael reaction was employed as a key …

We describe our efforts toward the total synthesis of the natural product elisabethin A. The
first route was guided by the proposed biosynthesis, assembling the 6, 6-ring system before …