Chemical modifications of DNA and RNA regulate genome functions or trigger mutagenesis
resulting in aging or cancer. Oxidations of macromolecules, including DNA, are common …

Recently, the sulfate radical (SO4•–) has been found to exhibit broad application prospects
in various research fields such as chemical, biomedical, and environmental sciences. It has …

The developmental toxicity of water disinfection byproducts remains unclear. Here we report
the study of halobenzoquinone (HBQ)-induced in vivo developmental toxicity and oxidative …

Halobenzoquinones (HBQs), a new class of disinfection byproducts (DBPs), occur widely in
treated drinking water and recreational water. The main concern regarding human exposure …

Long-term exposures to environmental toxicants are causative factors for human health
effects. DNA damages are of great interest in that they can serve as the potential biomarkers …

Most treatments for spinal cancer are accompanied by serious side effects including
subsequent tumor recurrence, spinal cord compression, and tissue adhesion, thus a highly …

DNA methylation has been proven to be a critical epigenetic mark important for various
cellular processes. Here, we report that redox-active quinones, a ubiquitous class of …

Dibromohydroquinone (2, 6-DBrHQ) has been identified as an reactive metabolite of many
brominated phenolic environmental pollutants such as tetrabromobisphenol-A (TBBPA) …

Structure-based DNA modification analysis provides accurate and important information on
genomic DNA changes from epigenetic modifications to various DNA lesions. However …

Halogenated quinones (XQ) are a class of carcinogenic intermediates and newly identified
chlorination disinfection byproducts in drinking water. Organic hydroperoxides (ROOH) can …