Genetics of human susceptibility to active and latent tuberculosis: present knowledge and future perspectives

L Abel, J Fellay, DW Haas, E Schurr… - The Lancet infectious …, 2018 - thelancet.com
Tuberculosis is an ancient human disease, estimated to have originated and evolved over
thousands of years alongside modern human populations. Despite considerable advances …

Prospects of toll‐like receptors in dairy cattle breeding

M Maurić Maljković, I Vlahek, A Piplica… - Animal …, 2023 - Wiley Online Library
Toll‐like receptors (TLRs) play an important role in mediating the immune response against
various microbes, such as bacteria, viruses, parasites, and fungi, in innate and adaptive …

Single nucleotide polymorphisms in the bovine TLR2 extracellular domain contribute to breed and species-specific innate immune functionality

MC Bartens, AJ Gibson, GJ Etherington… - Frontiers in …, 2021 - frontiersin.org
Recent evidence suggests that several cattle breeds may be more resistant to infection with
the zoonotic pathogen Mycobacterium bovis. Our data presented here suggests that the …

Association of TLR gene variants in a Czech Red Pied cattle population with reproductive traits

M Bjelka, K Novák - Veterinary immunology and immunopathology, 2020 - Elsevier
The bovine genes TLR1, TLR2 and TLR6, which encode Toll-like receptors, key
components of the innate immune system, were screened for polymorphisms in Czech Red …

Haplotype Disequilibrium in the TLR Genes of Czech Red Pied Cattle

K Samaké, K Novák - Diversity, 2023 - mdpi.com
Hybrid resequencing of the antibacterial innate immune genes coding for toll-like receptors,
namely TLR1, TLR2, TLR4, TLR5, and TLR6, using HiSeq and PacBio technologies of …

Survey of candidate single-nucleotide polymorphisms in SLC11A1, TLR4, NOD2, PGLYRP1, and IFNγ in Ankole Longhorn cattle in central region of Uganda to …

JB Okuni, M Afayoa, L Ojok - Frontiers in Veterinary Science, 2021 - frontiersin.org
Mycobacterium avium ssp. paratuberculosis (MAP) is the cause of Johne's disease (JD) in a
wide range of domestic and wild ruminants. Single-nucleotide polymorphisms (SNPs) in …

Potential of TLR-gene diversity in Czech indigenous cattle for resistance breeding as revealed by hybrid sequencing

K Novák, M Bjelka, K Samake… - Archives animal …, 2019 - aab.copernicus.org
A production herd of Czech Simmental cattle (Czech Red Pied, CRP), the conserved
subpopulation of this breed, and the ancient local breed Czech Red cattle (CR) were …

Genotypic structure of four cattle breeds raised in Turkey by loci related to several diseases

F Karayel, T Karslı - Mediterranean Agricultural Sciences, 2022 - dergipark.org.tr
This study aims to reveal the genotypic structure of four cattle breeds; Holstein (HS), Turkish
Grey Steppe (TGS), Anatolian Black (AB) and East Anatolian Red (EAR), raised in Turkey in …

[HTML][HTML] Association of single nucleotide polymorphisms in the fatty acid synthase, LOC514211, and fat mass and obesity-associated genes with milk traits in …

AP Rahayu, T Hartatik, A Purnomoadi… - Veterinary …, 2019 - ncbi.nlm.nih.gov
Aim: The study aimed to identify fatty acid synthase (FASN), LOC514211, and fat mass and
obesity-associated (FTO) gene polymorphisms and to investigate their associations with milk …

Association of TLR2 haplotypes encoding Q650 with reduced susceptibility to ovine Johne's disease in Turkish sheep

Y Yaman, R Aymaz, M Keleş, V Bay, C Ün… - Scientific Reports, 2021 - nature.com
Ovine Johne's disease (OJD) is caused by Mycobacterium avium subsp. paratuberculosis
(MAP) and carries a potential zoonotic risk for humans. Selective breeding strategies for …