Spatial proteomics is an interdisciplinary field that investigates the localization and dynamics
of proteins, and it has gained extensive attention in recent years, especially the subcellular …

INTRODUCTION A complete view of human biology can only be achieved by studying the
molecular components of its smallest functional unit, the cell. Cells are internally organized …

The study of protein localisation has greatly benefited from high-throughput methods
utilising cellular fractionation and proteomic profiling. Hyperplexed Localisation of Organelle …

Microbial pathogens have evolved numerous mechanisms to hijack host's systems, thus
causing disease. This is mediated by alterations in the combined host-pathogen proteome in …

Protein localisation and translocation between intracellular compartments underlie almost
all physiological processes. The hyperLOPIT proteomics platform combines mass …

The organization of eukaryotic cells into distinct subcompartments is vital for all functional
processes, and aberrant protein localization is a hallmark of many diseases. Microscopy …

Motivation The reconstruction of gene regulatory networks (GRNs) from gene expression
data has received increasing attention in recent years, due to its usefulness in the …

Abstract The reconstruction of Gene Regulatory Networks (GRNs) from gene expression
data, supported by machine learning approaches, has received increasing attention in …

Analysis of the spatial sub-cellular distribution of proteins is of vital importance to fully
understand context specific protein function. Some proteins can be found with a single …

The order of enzymatic activity across Golgi cisternae is essential for complex molecule
biosynthesis. However, an inability to separate Golgi cisternae has meant that the cisternal …