The past decade has witnessed exponentially growing interest in the lateral habenula (LHb)
owing to new discoveries relating to its critical role in regulating negatively motivated …

Abstinence from chronic use of addictive drugs triggers an aversive withdrawal syndrome
that compels relapse and deters abstinence. Many features of this syndrome are common …

Insomnia is a heritable, highly prevalent sleep disorder for which no sufficient treatment
currently exists. Previous genome-wide association studies with up to 1.3 million subjects …

Animals generate neural representations of their heading direction. Notably, in insects,
heading direction is topographically represented by the activity of neurons in the central …

In order to localize the neural circuits involved in generating behaviors, it is necessary to
assign activity onto anatomical maps of the nervous system. Using brain registration across …

The brain has persistent internal states that can modulate every aspect of an animal's mental
experience,,–. In complex tasks such as foraging, the internal state is dynamic …

Asymmetry of the brain and behaviour (lateralization) has traditionally been considered
unique to humans. However, research has shown that this phenomenon is widespread …

Prolonged behavioral challenges can cause animals to switch from active to passive coping
strategies to manage effort-expenditure during stress; such normally adaptive behavioral …

Most behaviors, even simple innate reflexes, are mediated by circuits of neurons spanning
areas throughout the brain. However, in most cases, the distribution and dynamics of firing …

The zebrafish dorsal habenula (dHb) shows conspicuous asymmetry in its connection with
the interpeduncular nucleus (IPN) and is equivalent to the mammalian medial habenula …