Epithelial ovarian cancer (EOC) is one of the cancers most influenced by hereditary factors.
A fourth to a fifth of unselected EOC patients carry pathogenic variants (PVs) in a number of …

Background A comprehensive examination of the incidence and mortality of subsequent
primary cancers (SPCs) among adolescent and young adult (AYA) cancer survivors in the …

Endometrial cancer (EC) is the most common gynecological malignancy in developed
countries. The present study aimed to determine the frequency of germline pathogenic …

Background Cancer susceptibility germline mutations are associated with pancreatic ductal
adenocarcinoma (PDAC). However, the hereditary status of PDAC and its impact on survival …

Purpose Herein, we report the frequency and distribution of germline pathogenic variants
(PVs) among females with breast cancer (BC) and at least one other non-BC who underwent …

Background: The development of medicine, especially in oncology, has been helping
prolong the cancer patients' survival, but also leads to increasing the possibility of getting …

Objectives To evaluate risk of a second cancer and associated survival times in United
States women with diagnosis of cancer. Methods The Surveillance Epidemiology and End …

Multiple primary tumors (MPTs) are a harbinger of hereditary cancer syndromes. Affected
individuals often fit genetic testing criteria for a number of hereditary cancer genes and …

Purpose As panel testing expands, more individuals with double pathogenic variants (DPVs)
in cancer susceptibility genes are likely to be identified. Little is known about the effects of …

Interventions: The patient was treated with azacitidine+ Veneckla chemotherapy, and
through precise regulation, the patient survived the period of bone marrow suppression. He …