Messenger RNA (mRNA) has emerged as a promising therapeutic agent for the prevention
and treatment of various diseases. mRNA vaccines, in particular, offer an alternative …

Simple Summary This review assesses the integration of nanotechnology and
immunotherapy, with a specific focus on the utilization of nanomaterials to modulate the …

Lipid nanoparticles (LNP) have emerged as pivotal delivery vehicles for RNA therapeutics.
Previous research and development usually assumed that LNPs are homogeneous in …

The success of lipid nanoparticles (LNPs) in treating COVID-19 promotes further research of
mRNA vaccines for cancer vaccination. Aiming at overcoming the constraints of currently …

Lipid nanoparticles (LNPs) have recently emerged as successful gene delivery platforms for
a diverse array of disease treatments. Efforts to optimize their design for common …

Combination immunotherapy is being increasingly explored for cancer treatment, leading to
various vector materials for the codelivery of immune agents and drugs. However, current …

Messenger ribonucleic acid (mRNA) has emerged as a promising molecular preventive and
therapeutic approach that opens new avenues for healthcare. Although the use of delivery …

Extracellular vesicles (EVs), especially exosomes, have shown great therapeutic potential in
the treatment of diseases, as they can target cells or tissues. However, the therapeutic effect …

For cell and gene therapies to become more broadly accessible, it is critical to develop and
optimize non-viral cell type-preferential gene carriers such as lipid nanoparticles (LNPs) …

The realm of cancer therapy has been profoundly altered with the emergence of immune
checkpoint blockade (ICB) therapy, providing improved survival prospects for many patients …