The biology of eosinophils and their role in asthma

CN McBrien, A Menzies-Gow - Frontiers in medicine, 2017 - frontiersin.org
This review will describe the structure and function of the eosinophil. The roles of several
relevant cell surface molecules and receptors will be discussed. We will also explore the …

Human toxocariasis: diagnosis, worldwide seroprevalences and clinical expression of the systemic and ocular forms

G Rubinsky-Elefant, CE Hirata… - Annals of Tropical …, 2010 - Taylor & Francis
Although human toxocariasis ranks among the most common zoonotic infections worldwide,
it remains relatively unknown to the public. The causal agents are the nematode parasites …

[HTML][HTML] Anti-inflammatory effect of quercetin-loaded microemulsion in the airways allergic inflammatory model in mice

AP Rogerio, CL Dora, EL Andrade, JS Chaves… - Pharmacological …, 2010 - Elsevier
Quercetin is a plant-derived flavonoid widely known by its anti-oxidant and anti-inflammatory
properties, but its oral bioavailability is very poor and this becomes difficult to assess its …

Anti-inflammatory effects of Lafoensia pacari and ellagic acid in a murine model of asthma

AP Rogerio, C Fontanari, É Borducchi, AC Keller… - European journal of …, 2008 - Elsevier
We have shown that the ethanolic extract of Lafoensia pacari inhibits eosinophilic
inflammation induced by Toxocara canis infection, and that ellagic acid is the secondary …

CARD9S12N facilitates the production of IL-5 by alveolar macrophages for the induction of type 2 immune responses

X Xu, JF Xu, G Zheng, HW Lu, JL Duan, W Rui… - Nature …, 2018 - nature.com
The adaptor CARD9 functions downstream of C-type lectin receptors (CLRs) for the sensing
of microbial infection, which leads to responses by the TH1 and TH17 subsets of helper T …

Natural killer T cells in allergic asthma: implications for the development of novel immunotherapeutical strategies

C Gutiérrez-Vera, R García-Betancourt… - Frontiers in …, 2024 - frontiersin.org
Allergic asthma has emerged as a prevalent allergic disease worldwide, affecting most
prominently both young individuals and lower-income populations in developing and …

Leukotrienes play a role in the control of parasite burden in murine strongyloidiasis

ER Machado, MT Ueta, EV Lourenço… - The Journal of …, 2005 - journals.aai.org
It is clear that leukotrienes mediate inflammatory response; new aspects of leukotriene
function have recently been described. In this study, we demonstrate that leukotrienes are …

[HTML][HTML] The activity of medicinal plants and secondary metabolites on eosinophilic inflammation

AP Rogerio, A Sá-Nunes, LH Faccioli - Pharmacological Research, 2010 - Elsevier
Eosinophils are leukocytes that are present in several body compartments and in the blood
at relatively low numbers under normal conditions. However, an increase in the number of …

Effects of oral exposure to low-dose Bisphenol S on allergic asthma in mice

R Yanagisawa, E Koike, TT Win-Shwe… - International Journal of …, 2022 - mdpi.com
Bisphenol S (BPS) is increasingly being used as an alternative for bisphenol A; however, its
health effects remain unclear. We investigated the effects of oral exposure to low-dose BPS …

Type 2 cytokine responses: regulating immunity to helminth parasites and allergic inflammation

EK Henry, JM Inclan-Rico, MC Siracusa - Current pharmacology reports, 2017 - Springer
Abstract Purpose of Review It is well established that T helper type 2 (TH 2) immune
responses are necessary not only to provide protection against helminth parasites but also …