As a controllable biological process, regulated cell death (RCD) extensively participates in
cellular homeostasis, organismal development, and the pathogenesis of diseases. This …

Lipid nanoparticles (liposomes) were first described in 1965, and several work have led to
development of important technical advances like triggered release liposomes and drug …

Recent studies have revealed that long noncoding RNA metastasis‐associated lung
adenocarcinoma transcript 1 (MALAT1) plays an important role in the development of …

Bupivacaine is frequently administered for diagnosing and controlling spine-related pain in
interventional spine procedures. However, the potential cytotoxic effects of bupivacaine on …

BACKGROUND: Although local anesthetics (LAs) are generally accepted as being safe,
incidental neuronal damage has been reported for all LAs in humans. Therefore, in this …

Background The important role of miR-455-3p in the pathogenesis of bone metabolism
associated diseases is gradually emerging. This study aims to ascertain the involvement of …

Local anaesthetics (LAs) may lead to neurological complications, but the underlying
mechanism is still unclear. Many neurotoxicity research studies have examined different …

Objective The purposes of this study were to assess whether local anesthetics (LAs), such
as ropivacaine and bupivacaine, could induce apoptosis of rabbit annulus fibrosus (AF) cells …

Several advancements have been made on the exact release of local anaesthetics
formulation and its efficiency at inducing motor and sensory block for an extended time has …

OBJECTIVE. Spinal injections are common pain management procedures using
corticosteroids and local anesthetics. Most corticosteroid preparations are particulate …