The immune system has to cope with a wide range of irregularly shaped pathogens that can
actively move (eg, by flagella) and also dynamically remodel their shape (eg, transition from …

Neutrophils are crucial elements of innate immune system, which assure host defense via a
range of effector functions, such as phagocytosis, degranulation, and NET formation. The …

Heterodimeric capping protein (CP/CapZ) is an essential factor for the assembly of branched
actin networks, which push against cellular membranes to drive a large variety of cellular …

Phagocytic clearance of dying cells, termed efferocytosis, is essential for maintaining tissue
homeostasis, yet our understanding of efferocytosis regulation remains incomplete. Here we …

Phagocytosis requires rapid actin reorganization and spatially controlled force generation to
ingest targets ranging from pathogens to apoptotic cells. How actomyosin activity directs …

Actin filaments play multiple roles in the secretory pathway and in endosome dynamics in
mammals, including maintenance of Golgi structure, release of membrane cargo from the …

Macrophages are key immune cells with important roles for tissue surveillance in almost all
mammalian organs. Cellular networks made up of many individual macrophages allow for …

Phagocytosis is a cellular process maintaining tissue balance and plays an essential role in
initiating the innate immune response. The process of phagocytosis was triggered by the …

Macrophages are essential in the initiation, maintenance, and transition of inflammatory
processes such as foreign body response and wound healing. Mounting evidence suggests …

Peptide coacervates self‐assembling via liquid‐liquid phase separation are appealing
intracellular delivery vehicles of macromolecular therapeutics (proteins, DNA, mRNA) owing …