This review comprehensively summarizes recent advances in the field of
hydrazinecarboxamide (semicarbazide) derivatives, highlighting their significant therapeutic …

Hydrazinecarboxamides (semicarbazides) are increasingly recognized as a versatile
scaffold in developing potential antimicrobial agents. In addition to a brief overview of the …

A series of novel coumarin thiazoles containing trifluoromethyl group 3a-3l were prepared
through a one-pot reaction using 3-(trifluoroacetyl) coumarin as a starting material in solvent …

Based on the broad spectrum of biological activity of hydrazide–hydrazones, trifluoromethyl
compounds, and clinical usage of cholinesterase inhibitors, we investigated hydrazones …

Mycobacterium tuberculosis is an intracellular pathogen and the uptake of the
antimycobacterial compounds by host cells is limited. Novel antimycobacterials effective …

A series of halogenated 3-hydroxyflavones (3HFs)(3a-3f) and their conjugates with two
trifluoroacetylated amino acids, namely glycine and L-alanine, were synthesized and …

2, 5-Disubstituted 1, 3, 4-oxadiazoles are privileged versatile scaffolds in medicinal
chemistry that have exhibited diverse biological activities. Acetyl-(AChE) and …

Background: Hydrazide-hydrazones have been known as scaffold with various biological
activities including inhibition of acetyl-(AChE) and butyrylcholinesterase (BuChE) …

A detailed theoretical and experimental study was implemented on a novel bioactive
molecule 2-(3-bromobenzoyl)-N-methylhydrazine-1-carboxamide (BMC). Density Functional …

Tragopogon dubius is commonly consumed as a vegetable and used in traditional medicine
for treating inflammatory skin conditions and cutaneous swelling. Despite known …