Synthesis, anticancer activity, toxicity evaluation and molecular docking studies of novel phenylaminopyrimidine—(thio) urea hybrids as potential kinase inhibitors

A Türe, DC Kahraman, R Cetin-Atalay… - … biology and chemistry, 2019 - Elsevier
Thirty-two novel urea/thiourea compounds as potential kinase inhibitor were designed,
synthesized and evaluated for their cytotoxic activity on breast (MCF7), colon (HCT116) and …

Enzyme inhibitory, antioxidant and antibacterial potentials of synthetic symmetrical and unsymmetrical thioureas

S Naz, M Zahoor, MN Umar, B Ali, R Ullah… - Drug Design …, 2019 - Taylor & Francis
Background In this study, 2 symmetrical and 3 unsymmetrical thioureas were synthesized to
evaluate their antioxidant, antibacterial, antidiabetic, and anticholinesterase potentials …

Unclicking of thioureas: Base catalyzed elimination of anilines and isothiocyanates from thioureas

M Vlatković, BL Feringa - Tetrahedron, 2019 - Elsevier
Bisaromatic thioureas are widely used in eg asymmetric organocatalysis and considered to
be robust compounds. Herein we show, in strong contrast to common notion, that thioureas …

Dynamic control of chiral space

M Vlatković - 2016 - research.rug.nl
Responsive molecular systems are systems, which upon external stimuli; produce
observable changes of physical or chemical properties. Those changes are typically the …

[引用][C] FENĠLAMĠNOPĠRĠMĠDĠN TÜREVĠ BAZI YENĠ BĠLEġĠKLERĠN TASARIMI, SENTEZĠ VE ANTĠKANSER ETKĠLERĠNĠN DEĞERLENDĠRĠLMESĠ

A DEMĠRCĠ