Marine natural products
Covering: 2004. Previous review: Nat. Prod. Rep., 2005, 22, 15This review covers the
literature published in 2004 for marine natural products, with 693 citations (491 for the …
literature published in 2004 for marine natural products, with 693 citations (491 for the …
Histone deacetylase inhibitors: from bench to clinic
M Paris, M Porcelloni, M Binaschi… - Journal of medicinal …, 2008 - ACS Publications
The interest in histone deacetylase (HDACa) inhibitors began almost 30 years ago during
some studies designed to understand why dimethyl sulfoxide (DMSO) caused terminal …
some studies designed to understand why dimethyl sulfoxide (DMSO) caused terminal …
HDAC as onco target: Reviewing the synthetic approaches with SAR study of their inhibitors
Even though one is moving towards the success in the discovery of efficient anti-cancer
molecules, the drugs used in the treatment of various malignancies are found to possess …
molecules, the drugs used in the treatment of various malignancies are found to possess …
Marine pharmacology in 2003–2004: anti-tumour and cytotoxic compounds
AMS Mayer, KR Gustafson - European Journal of Cancer, 2006 - Elsevier
During 2003 and 2004, marine pharmacology research directed towards the discovery and
development of novel anti-tumour agents was published in 163 peer-reviewed articles. The …
development of novel anti-tumour agents was published in 163 peer-reviewed articles. The …
Feijoa sellowiana derived natural Flavone exerts anti-cancer action displaying HDAC inhibitory activities
P Bontempo, L Mita, M Miceli, A Doto… - The international journal …, 2007 - Elsevier
Curative properties of some medicinal plants such as the Feijoa sellowiana
Bert.(Myrtaceae), have been often claimed, although the corresponding molecular …
Bert.(Myrtaceae), have been often claimed, although the corresponding molecular …
A comprehensive review of marine sponge metabolites, with emphasis on Neopetrosia sp.
N Barzkar, S Sukhikh, O Babich - International Journal of Biological …, 2024 - Elsevier
The secondary metabolites that marine sponges create are essential to the advancement of
contemporary medicine and are often employed in clinical settings. Over the past five years …
contemporary medicine and are often employed in clinical settings. Over the past five years …
Non-hydroxamate histone deacetylase inhibitors
T Suzuki, N Miyata - Frontiers in Medicinal Chemistry: Volume 4, 2009 - benthamdirect.com
A number of histone deacetylase (HDAC) inhibitors have been developed as anticancer
agents and most of them are hydroxamic acid derivatives, typified by suberoylanilide …
agents and most of them are hydroxamic acid derivatives, typified by suberoylanilide …
Macrocyclic histone deacetylase inhibitors
SC Mwakwari, V Patil, W Guerrant… - Current topics in …, 2010 - ingentaconnect.com
Histone deacetylase inhibitors (HDACi) are an emerging class of novel anti-cancer drugs
that cause growth arrest, differentiation, and apoptosis of tumor cells. In addition, they have …
that cause growth arrest, differentiation, and apoptosis of tumor cells. In addition, they have …
Potential of synthetic and natural compounds as novel histone deacetylase inhibitors for the treatment of hematological malignancies
Simple Summary Histone deacetylases (HDACs) are epigenetic regulators that influence
chromatin structure and gene transcription, but also the function of non-histone targets like …
chromatin structure and gene transcription, but also the function of non-histone targets like …
Azumamides A–E: Histone Deacetylase Inhibitory Cyclic Tetrapeptides from the Marine Sponge Mycale izuensis
Y Nakao, S Yoshida, S Matsunaga… - Angewandte Chemie …, 2006 - Wiley Online Library
Histone acetylation and deacetylation, which are catalyzed by histone acetyltransferases
(HATs) and histone deacetylases (HDACs), respectively, play important roles in …
(HATs) and histone deacetylases (HDACs), respectively, play important roles in …