Abstract Although antibodies against Glutamic Acid Decarboxylase (GAD) were originally associated with Stiff Person Syndrome (SPS), they now denote the “GAD antibody-spectrum …
P Tsiortou, H Alexopoulos… - Therapeutic advances in …, 2021 - journals.sagepub.com
Antibodies against glutamic acid decarboxylase (GAD), originally linked to stiff person syndrome (SPS), now denote the “GAD antibody-spectrum disorders”(GAD-SD) that also …
V Lampasona, D Liberati - Current diabetes reports, 2016 - Springer
Islet autoantibodies are the main markers of pancreatic autoimmunity in type 1 diabetes (T1D). Islet autoantibodies recognize insulin (IAA), glutamic acid decarboxylase (GADA) …
JF Baizabal-Carvallo - Journal of autoimmunity, 2019 - Elsevier
A number of neurological syndromes have been described in patients with positive serum antibodies (Abs) against the enzyme glutamic acid decarboxylase (GAD), the rate limiting …
F Zhang, X Gao, J Liu, C Zhang - Frontiers in immunology, 2023 - frontiersin.org
The autoimmune diseases of the central nervous system (CNS) represent individual heterogeneity with different disease entities. Although clinical and imaging features make it …
M Li, LJ Song, XY Qin - Journal of cellular and molecular …, 2014 - Wiley Online Library
Type 1 diabetes is an autoimmune disease caused by the immune‐mediated destruction of insulin‐producing pancreatic β cells. In recent years, the incidence of type 1 diabetes …
F Ali, M Rowley, B Jayakrishnan, S Teuber… - Journal of …, 2011 - Elsevier
Stiff Person Syndrome (SPS) is a rare autoimmune neurological disease attributable to autoantibodies to glutamic acid decarboxylase (anti-GAD) more usually associated with the …
MC Dalakas - Nature Reviews Neurology, 2024 - nature.com
Stiff-person syndrome (SPS) is the prototypical and most common autoimmune neuronal hyperexcitability disorder. It presents with stiffness in the limbs and axial muscles, stiff gait …
M Gold, R Pul, JP Bach, M Stangel… - Immunological …, 2012 - Wiley Online Library
In this article, we review the current knowledge on pathological and physiological autoantibodies directed toward structures in the central nervous system (CNS) with an …