Reticular pseudodrusen: a critical phenotype in age-related macular degeneration

Z Wu, EL Fletcher, H Kumar, U Greferath… - Progress in retinal and …, 2022 - Elsevier
Reticular pseudodrusen (RPD), or subretinal drusenoid deposits (SDD), refer to distinct
lesions that occur in the subretinal space. Over the past three decades, their presence in …

OCT angiography and evaluation of the choroid and choroidal vascular disorders

E Borrelli, D Sarraf, KB Freund, SR Sadda - Progress in retinal and eye …, 2018 - Elsevier
The recent introduction of optical coherence tomography angiography (OCTA) has
remarkably expanded our knowledge of the choroid through in vivo investigation of the …

Subretinal drusenoid deposits AKA pseudodrusen

RF Spaide, S Ooto, CA Curcio - Survey of ophthalmology, 2018 - Elsevier
A distinction between conventional drusen and pseudodrusen was first made in 1990, and
more recently knowledge of pseudodrusen, more accurately called subretinal drusenoid …

Investigating the choriocapillaris and choroidal vasculature with new optical coherence tomography technologies

D Ferrara, NK Waheed, JS Duker - Progress in retinal and eye research, 2016 - Elsevier
The body of knowledge of in vivo investigation of the choroid has been markedly enhanced
by recent technological advances in optical coherence tomography (OCT). New insights …

Impairments in dark adaptation are associated with age-related macular degeneration severity and reticular pseudodrusen

J Flamendorf, E Agrón, WT Wong, D Thompson… - Ophthalmology, 2015 - Elsevier
Purpose We investigate whether ocular and person-based characteristics were associated
with dark adaptation (DA). Design Cross-sectional, single-center, observational study …

[HTML][HTML] Endpoints for clinical trials in ophthalmology

L Schmetterer, H Scholl, G Garhöfer… - Progress in Retinal and …, 2023 - Elsevier
With the identification of novel targets, the number of interventional clinical trials in
ophthalmology has increased. Visual acuity has for a long time been considered the gold …

[HTML][HTML] Association between geographic atrophy progression and reticular pseudodrusen in eyes with dry age-related macular degeneration

M Marsiglia, S Boddu, S Bearelly, L Xu… - … & visual science, 2013 - jov.arvojournals.org
Purpose.: To evaluate geographic atrophy (GA) progression in eyes with dry AMD and to
determine factors related to GA expansion, notably reticular pseudodrusen (RPD), also …

Choriocapillaris nonperfusion is associated with poor visual acuity in eyes with reticular pseudodrusen

PL Nesper, BT Soetikno, AA Fawzi - American journal of ophthalmology, 2017 - Elsevier
Purpose To study choriocapillaris blood flow in age-related macular degeneration (AMD)
using optical coherence tomography angiography (OCTA) and study its correlation to visual …

Quantitative fundus autofluorescence in early and intermediate age-related macular degeneration

M Gliem, PL Müller, RP Finger… - JAMA …, 2016 - jamanetwork.com
Importance Increased lipofuscin accumulation is assumed to be an important factor in the
pathogenesis of age-related macular degeneration (AMD), although direct evidence for this …

[HTML][HTML] Correlation of histologic features with in vivo imaging of reticular pseudodrusen

U Greferath, RH Guymer, KA Vessey, K Brassington… - Ophthalmology, 2016 - Elsevier
Purpose To determine the histologic and cellular correlates in the retina and retinal pigment
epithelium (RPE) with the presence of optical coherence tomography-defined reticular …