Gold nanoparticles (GNPs) in biomedical and clinical applications: A review

MI Anik, N Mahmud, A Al Masud, M Hasan - Nano Select, 2022 - Wiley Online Library
Gold nanoparticles (GNPs) have been extensively used in various applications ranging from
environmental detection to biomedical applications. Due to their unique characteristics such …

Radioactive polymeric nanoparticles for biomedical application

S Wu, E Helal-Neto, APS Matos, A Jafari… - Drug Delivery, 2020 - Taylor & Francis
Nowadays, emerging radiolabeled nanosystems are revolutionizing medicine in terms of
diagnostics, treatment, and theranostics. These radionuclides include polymeric …

Polymer-stabilized elemental boron nanoparticles for boron neutron capture therapy: Initial irradiation experiments

A Zaboronok, P Khaptakhanova, S Uspenskii… - Pharmaceutics, 2022 - mdpi.com
Sufficient boron-10 isotope (10B) accumulation by tumor cells is one of the main
requirements for successful boron neutron capture therapy (BNCT). The inability of the …

Nanoparticles and radioisotopes: a long story in a nutshell

G Poletto, L Evangelista, F Venturini, F Gramegna… - Pharmaceutics, 2022 - mdpi.com
The purpose of this narrative review was to assess the use of nanoparticles (NPs) to deliver
radionuclides to targets, focusing on systems that have been tested in pre-clinical and, when …

Gold nanoparticles permit in situ absorbed dose evaluation in boron neutron capture therapy for malignant tumors

A Zaboronok, S Taskaev, O Volkova, L Mechetina… - Pharmaceutics, 2021 - mdpi.com
Boron neutron capture therapy (BNCT) is an anticancer modality realized through 10B
accumulation in tumor cells, neutron irradiation of the tumor, and decay of boron atoms with …

Radiolabeled Human Serum Albumin Nanoparticles Co-Loaded with Methotrexate and Decorated with Trastuzumab for Breast Cancer Diagnosis

M Ekinci, LMR Alencar, AM Lopes… - Journal of Functional …, 2023 - mdpi.com
Breast cancer is a leading cause of cancer-related mortality among women worldwide, with
millions of new cases diagnosed yearly. Addressing the burden of breast cancer mortality …

Glutathione disulfide as a reducing, capping, and mass-separating agent for the synthesis and enrichment of gold nanoclusters

Q Zhang, J Wang, Z Meng, R Ling, H Ren, W Qin, Z Wu… - Nanomaterials, 2021 - mdpi.com
Water-soluble nanoclusters, which are facilely enrichable without changes in the original
properties, are highly demanded in many disciplines. In this contribution, a new class of gold …

Development of MRI-Detectable Boron-Containing Gold Nanoparticle-Encapsulated Biodegradable Polymeric Matrix for Boron Neutron Capture Therapy (BNCT)

CY Wu, HH Hsieh, TY Chang, JJ Lin, CC Wu… - International Journal of …, 2021 - mdpi.com
This study aimed to develop a novel magnetic resonance imaging (MRI)-detectable boron
(B)-containing nanoassemblies and evaluate their potential for boron neutron capture …

Multimodal radiolabeled gold nanoparticle molecular probes: synthesis, imaging, and applications

Q Gao, F Chen - Journal of Radioanalytical and Nuclear Chemistry, 2023 - Springer
Recent years have witnessed increasing advances in gold nanoparticles (GNPs) for
accurate and precise diagnosis and therapy. GNPs have great potential in translating into …

Radiation nanomedicines for cancer treatment: a scientific journey and view of the landscape

RM Reilly, CJ Georgiou, MK Brown, Z Cai - EJNMMI Radiopharmacy and …, 2024 - Springer
Background Radiation nanomedicines are nanoparticles labeled with radionuclides that
emit α-or β-particles or Auger electrons for cancer treatment. We describe here our 15 years …