Chitosan as biomaterial in drug delivery and tissue engineering

SM Ahsan, M Thomas, KK Reddy… - International journal of …, 2018 - Elsevier
Chitin is one of the most abundant polysaccharide found on earth. The deacetylated form of
chitin viz. chitosan has been reported for its various important pharmacological properties …

Preparation, characterization, and potential application of chitosan, chitosan derivatives, and chitosan metal nanoparticles in pharmaceutical drug delivery

TA Ahmed, BM Aljaeid - Drug design, development and therapy, 2016 - Taylor & Francis
Naturally occurring polymers, particularly of the polysaccharide type, have been used
pharmaceutically for the delivery of a wide variety of therapeutic agents. Chitosan, the …

Recent trends on gellan gum blends with natural and synthetic polymers: A review

KM Zia, S Tabasum, MF Khan, N Akram… - International Journal of …, 2018 - Elsevier
Gellan gum (GG), a linear negatively charged exopolysaccharide, is biodegradable and non-
toxic in nature. It produces hard and translucent gel in the presence of metallic ions which is …

Potential of insulin nanoparticle formulations for oral delivery and diabetes treatment

CY Wong, H Al-Salami, CR Dass - Journal of controlled release, 2017 - Elsevier
Nanoparticles have demonstrated significant advancements in potential oral delivery of
insulin. In this publication, we review the current status of polymeric, inorganic and solid-lipid …

Chitosan-based delivery systems for protein therapeutics and antigens

M Amidi, E Mastrobattista, W Jiskoot… - Advanced drug delivery …, 2010 - Elsevier
Therapeutic peptides/proteins and protein-based antigens are chemically and structurally
labile compounds, which are almost exclusively administered by parenteral injections …

Protein–polyelectrolyte interactions

AB Kayitmazer, D Seeman, BB Minsky, PL Dubin, Y Xu - Soft Matter, 2013 - pubs.rsc.org
The interactions of proteins and polyelectrolytes lead to diverse applications in separations,
delivery and wound repair, and are thus of interest to scientists in eg (a) glycobiology,(b) …

Advances in self-assembled chitosan nanomaterials for drug delivery

Y Yang, S Wang, Y Wang, X Wang, Q Wang… - Biotechnology …, 2014 - Elsevier
Nanomaterials based on chitosan have emerged as promising carriers of therapeutic agents
for drug delivery due to good biocompatibility, biodegradability, and low toxicity. Chitosan …

Chitosan-catechol: A polymer with long-lasting mucoadhesive properties

K Kim, K Kim, JH Ryu, H Lee - Biomaterials, 2015 - Elsevier
Numerous mucoadhesive polymers have been exploited for prolonging the residence time
of formulated drugs or pharmaceuticals at specific delivery sites. However, it has been …

Nanoparticle delivery systems in the treatment of diabetes complications

EB Souto, SB Souto, JR Campos, P Severino… - Molecules, 2019 - mdpi.com
Diabetes mellitus, an incurable metabolic disease, is characterized by changes in the
homeostasis of blood sugar levels, being the subcutaneous injection of insulin the first line …

Drug permeability and mucoadhesion properties of thiolated trimethyl chitosan nanoparticles in oral insulin delivery

L Yin, J Ding, C He, L Cui, C Tang, C Yin - Biomaterials, 2009 - Elsevier
Trimethyl chitosan-cysteine conjugate (TMC-Cys) was synthesized in an attempt to combine
the mucoadhesion and the permeation enhancing effects of TMC and thiolated polymers …