Regulated cell death (RCD) is pivotal in directing the severity and outcome of liver injury.
Hepatocyte cell death is a critical event in the progression of liver disease due to resultant …

Atherosclerosis is a chronic inflammatory disorder characterized by the gradual buildup of
plaques within the vessel wall of middle-sized and large arteries. The occurrence and …

Acetaminophen (APAP)-induced liver injury (AILI) is a common liver disease in clinical
practice. Only one clinically approved drug, N-acetylcysteine (NAC), for the treatment of AILI …

Acetaminophen (APAP) overdose is a leading cause of drug-induced liver injury (DILI). The
impact of the gut microbiota and associated metabolites on APAP and liver function remains …

Ferroptosis, a newly characterized form of regulated cell death, is induced by excessive
accumulation of lipid peroxidation catalyzed by intracellular bioactive iron. Increasing …

Wogonoside (WG) is a flavonoid chemical component extracted from Scutellaria baicalensis,
which exerts therapeutic effects on liver diseases. Ferroptosis, a novel form of programmed …

Type 2 diabetic osteoporosis (T2DOP) is a chronic bone metabolic disease. Compared with
traditional menopausal osteoporosis, the long-term high glucose (HG) microenvironment …

Excessive iron has emerged in a large population of patients suffering from degenerative or
hematological diseases with a common outcome, osteoporosis. However, its underlying …

Acetaminophen (APAP)-induced liver injury (AILI) has become a growing public health
problem. Ferroptosis, an iron-dependent form of cell death associated with lipid peroxide …

Background Acute liver failure (ALF) is a syndrome of severe hepatocyte injury with high rate
of mortality. Hepatitis B virus (HBV) infection is the major cause of ALF worldwide, however …