Chagas cardiomyopathy: an update of current clinical knowledge and management: a scientific statement from the American Heart Association

MCP Nunes, A Beaton, H Acquatella, C Bern… - Circulation, 2018 - Am Heart Assoc
Background: Chagas disease, resulting from the protozoan Trypanosoma cruzi, is an
important cause of heart failure, stroke, arrhythmia, and sudden death. Traditionally …

Pathogenesis of chagas' disease: parasite persistence and autoimmunity

ARL Teixeira, MM Hecht, MC Guimaro… - Clinical microbiology …, 2011 - Am Soc Microbiol
Acute Trypanosoma cruzi infections can be asymptomatic, but chronically infected
individuals can die of Chagas' disease. The transfer of the parasite mitochondrial kinetoplast …

Chagas disease and stroke

FJ Carod-Artal, J Gascon - The Lancet Neurology, 2010 - thelancet.com
Chagas disease is a neglected infectious disease in the tropics and an emerging health
problem in Europe and the USA. In the past decade, a link has been recorded between …

Heart failure in South America

EA Bocchi - Current cardiology reviews, 2013 - ingentaconnect.com
Continued assessment of temporal trends in mortality and epidemiology of specific heart
failure in South America is needed to provide a scientific basis for rational allocation of the …

Chagasic cardiomyopathy is independently associated with ischemic stroke in Chagas disease

FJ Carod-Artal, AP Vargas, TA Horan, LGN Nunes - Stroke, 2005 - Am Heart Assoc
Background and Purpose—Chagasic cardiomyopathy is independently associated with
ischemic stroke in Chagas disease. American trypanosomiasis, Chagas disease (CD), is a …

Epidemiology of mortality related to Chagas' disease in Brazil, 1999–2007

FR Martins-Melo, CH Alencar… - PLoS neglected …, 2012 - journals.plos.org
Background Chagas' disease is an important neglected public health problem in many Latin
American countries, but population-based epidemiological data are scarce. Here we present …

Developments in the management of Chagas cardiomyopathy

HB Tanowitz, FS Machado, DC Spray… - Expert review of …, 2015 - Taylor & Francis
Over 100 years have elapsed since the discovery of Chagas disease and there is still much
to learn regarding pathogenesis and treatment. Although there are antiparasitic drugs …

Implantable cardioverter defibrillators and Chagas' disease: results of the ICD Registry Latin America

CA Muratore, LA Batista Sa, PA Chiale, R Eloy… - Europace, 2009 - academic.oup.com
Aims Chagas' disease is an endemic parasitic affliction in Latin America. It is frequently
associated with ventricular tachyarrhythmia and sudden death. The aim of this study is to …

Prevalence and risk factors of embolic cerebrovascular events associated with Chagas heart disease

MCP Nunes, LJ Kreuser, AL Ribeiro, GR Sousa… - Global heart, 2015 - Elsevier
Abstract Background Patients with Chagas disease are at increased risk for stroke that may
result in major clinical disability and death. Identification of risk factors involved in the …

Central nervous system involvement in Chagas disease: a hundred-year-old history

JEH Pittella - Transactions of the Royal Society of Tropical …, 2009 - academic.oup.com
This review gives an account of central nervous system (CNS) involvement in Chagas
disease, as confirmed by pathological studies. The fundamental histopathological finding …