Biotoxin detection using cell-based sensors

P Banerjee, S Kintzios, B Prabhakarpandian - Toxins, 2013 - mdpi.com
Cell-based biosensors (CBBs) utilize the principles of cell-based assays (CBAs) by
employing living cells for detection of different analytes from environment, food, clinical, or …

Electrochemical immunosensor for botulinum neurotoxin type-E using covalently ordered graphene nanosheets modified electrodes and gold nanoparticles-enzyme …

J Narayanan, MK Sharma, S Ponmariappan… - Biosensors and …, 2015 - Elsevier
In this work, a novel electrochemical immunosensor was developed for the detection of
botulinum neurotoxin-E (BoNT/E). This method relied on graphene nanosheets …

Recent developments in cell-based assays and stem cell technologies for botulinum neurotoxin research and drug discovery

E Kiris, KP Kota, JC Burnett, V Soloveva… - Expert review of …, 2014 - Taylor & Francis
Botulinum neurotoxins (BoNTs) are exceptionally potent inhibitors of neurotransmission,
causing muscle paralysis and respiratory failure associated with the disease botulism …

Biosensors in evaluation of quality of meat and meat products–A review

B Sionek, W Przybylski, K Tambor - Annals of Animal Science, 2020 - sciendo.com
Biosensors can find application in meat and meat products testing for safety, including
microbial and other contaminants, and quality, including meat freshness, beef tenderness …

[PDF][PDF] Methods and difficulties in detection of Clostridium botulinum and its toxins

T Grenda, E Kukier, K Kwiatek - Polish journal of veterinary …, 2014 - bibliotekanauki.pl
The aim of this work was to present selected data regarding traditional and modern methods
for C. botulinum and its toxins detection. In this article, methods based on culturing …

Content/potency assessment of botulinum neurotoxin type-A by validated liquid chromatography methods and bioassays

B Xavier, RF Perobelli, ME Walter, FS da Silva… - Toxins, 2019 - mdpi.com
Botulinum neurotoxin type-A (BoNTA) is one of the seven different serotypes (A to G)
produced by Clostridium botulinum. A stability-indicating size-exclusion chromatography …

Assessment of pesticides cytoxicity by means of bioelectric profiling of mammalian cells

G Moschopoulou, AM Dourou, A Fidaki… - Environmental …, 2017 - Elsevier
In the present study an innovative tool was performed for assessing pesticide cytoxicity of
different pesticide groups by using the bioelectric response patterns of neuroblastoma and …

Development of aequorin-based mast cell nanosensor for rapid identification of botulinum neurotoxin type B

W Xin, W Yao, X Gao, Z You, S Gao… - Journal of …, 2014 - ingentaconnect.com
An aequorin-based mast cell sensor was developed for rapid identification and detection of
protein toxins. To monitor mast cell activation and to improve the sensitivity of detection …

Technologies for detecting botulinum neurotoxins in biological and environmental matrices

W Cheng, M Land, C Tam, DL Brandon… - … and Control of Food …, 2016 - books.google.com
Biomonitoring of food and environmental matrices is critical for the rapid and sensitive
diagnosis, treatment, and prevention of diseases caused by toxins. The US Centers for …

Evaluation of botulinum toxin type A by bioassays and a validated reversed-phase liquid chromatography method

GW de Freitas, RF Perobelli, FPS Maldaner… - Analytical …, 2016 - pubs.rsc.org
The biological potency of botulinum toxin type A (BoNTA) in biotechnology-derived products
was assessed by the mouse LD50 bioassay (MBA) and the T47D cell culture assay. A …