Parkinson's disease (PD) is characterized by a range of motor symptoms. Besides the
cardinal symptoms (akinesia and bradykinesia, tremor and rigidity), PD patients show …

Parkinson's disease is a chronic progressive neurodegenerative disorder characterized by
resting tremor, slowness of movements, rigidity, gait disturbance and postural instability …

Importance It is increasingly evident that Parkinson disease (PD) is not a single entity but
rather a heterogeneous neurodegenerative disorder. Objective To evaluate available …

Abstract Parkinson's disease (PD), one of the most frequent neurodegenerative disorders, is
no longer considered a complex motor disorder characterized by extrapyramidal symptoms …

Classical accounts of the pathophysiology of Parkinson's disease have emphasized
degeneration of dopaminergic nigrostriatal neurons with consequent dysfunction of cortico …

Like many neurodegenerative disorders, Parkinson's disease (PD) is clinically highly
heterogeneous. A number of studies have proposed and defined subtypes of PD based on …

The concept of synergy provides a theoretical framework for movement stability resulting
from the neural organization of multiple elements (digits, muscles, etc.) that all contribute to …

Resting-state functional magnetic resonance imaging (RS-fMRI) studies have been
extensively applied to analyze the pathophysiology of neurodegenerative disorders such as …

Introduction: The axial symptoms of Parkinson disease (PD) include difficulties with balance,
posture, speech, swallowing, and locomotion with freezing of gait, as well as axial rigidity …

In this study, we tested several hypotheses related to changes in finger interaction and
multifinger synergies during multifinger force production tasks in Parkinson's disease. Ten …