Müller glia are the major glial component of the retina. They are one of the last retinal cell
types to be born during development, and they function to maintain retinal homeostasis and …

Müller cells, the major type of glial cells in the retina, are responsible for the homeostatic and
metabolic support of retinal neurons. By mediating transcellular ion, water, and bicarbonate …

Müller cells are active players in normal retinal function and in virtually all forms of retinal
injury and disease. Reactive Müller cells protect the tissue from further damage and …

In humans, various genetic defects or age-related diseases, such as diabetic retinopathies,
glaucoma, and macular degeneration, cause the death of retinal neurons and profound …

Neuronal progenitors in the mammalian brain derive from radial glia or specialized
astrocytes. In developing neural retina, radial glia-like Müller cells are generated late in …

Adult zebrafish generate new neurons in the brain and retina throughout life. Growth-related
neurogenesis allows a vigorous regenerative response to damage, and fish can regenerate …

Background The persistence in adult teleost fish of retinal stem cells that exhibit all of the
features of true'adult stem cells'–self-renewal, multipotency, and the capacity to respond to …

α1 tubulin (α1T) is a neuron-specific microtubule protein whose expression is induced in the
developing and regenerating CNS. In the adult CNS, α1T expression remains high in neural …

Background BM-derived mesenchymal stem cells (MSC) are attractive sources for
autotransplantation with no risk of rejection, but the use of these cells has problems …

Intense light exposure causes photoreceptor apoptosis in dark-adapted adult albino
zebrafish (Danio rerio). Subsequently, Müller glia increase expression of the Achaete-scute …