Pathophysiological mechanisms of thrombosis in acute and long COVID-19

H Jing, X Wu, M Xiang, L Liu, VA Novakovic… - Frontiers in …, 2022 - frontiersin.org
COVID-19 patients have a high incidence of thrombosis, and thromboembolic complications
are associated with severe COVID-19 and high mortality. COVID-19 disease is associated …

Platelet in thrombo-inflammation: Unraveling new therapeutic targets

S Sharma, T Tyagi, S Antoniak - Frontiers in immunology, 2022 - frontiersin.org
In the broad range of human diseases, thrombo-inflammation appears as a clinical
manifestation. Clinically, it is well characterized in context of superficial thrombophlebitis that …

[HTML][HTML] Drugs targeting adenosine signaling pathways: A current view

B Kutryb-Zając, A Kawecka, K Nasadiuk… - Biomedicine & …, 2023 - Elsevier
Adenosine is an endogenous nucleoside that regulates many physiological and
pathological processes. It is derived from either the intracellular or extracellular …

Use of antioxidants for the neuro-therapeutic management of COVID-19

N Cardenas-Rodriguez, C Bandala, A Vanoye-Carlo… - Antioxidants, 2021 - mdpi.com
Coronavirus Disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome
Coronavirus 2 (SARS-CoV-2), is an emergent infectious disease that has caused millions of …

Prevention and management of thrombosis in hospitalised patients with COVID-19 pneumonia

JL Vincent, M Levi, BJ Hunt - The Lancet Respiratory Medicine, 2022 - thelancet.com
A proportion of people infected with SARS-CoV-2 develop moderate or severe COVID-19,
with an increased risk of thromboembolic complications. The inflammatory response to …

Drugs for the prevention and treatment of COVID-19 and its complications: An update on what we learned in the past 2 years

G Remuzzi, S Schiaffino, MG Santoro… - Frontiers in …, 2022 - frontiersin.org
The COVID-19 Committee of the Lincei Academy has reviewed the scientific evidence
supporting the efficacy and safety of existing and new drugs/biologics for the preventing and …

The role of platelets, neutrophils and endothelium in COVID-19 infection

E Falcinelli, E Petito, P Gresele - Expert Review of Hematology, 2022 - Taylor & Francis
Introduction COVID-19 is associated to an increased risk of thrombosis, as a result of a
complex process that involves the activation of vascular and circulating cells, the release of …

[HTML][HTML] Acute myocardial injury in patients with COVID-19: Possible mechanisms and clinical implications

I Rusu, M Turlacu, MM Micheu - World Journal of Clinical Cases, 2022 - ncbi.nlm.nih.gov
Severe acute respiratory syndrome coronavirus 2 infection affects not only the lungs, but
also the cardiovascular system, having a major impact on patients' outcomes. Myocardial …

Purinergic signaling: Decoding its role in COVID-19 pathogenesis and promising treatment strategies

Z Shafaghat, AHK Ghomi, H Khorramdelazad… - …, 2023 - Springer
The pathogenesis of coronavirus disease (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS‑CoV‑2), is complex and involves dysregulated immune …

Enhancement of solubility and dissolution rate of dipyridamole by salifying: Preparation, characterization, and theoretical calculation

D Yi, Y Dong, Y Yao, M Hong, B Zhu, GB Ren… - Journal of Molecular …, 2024 - Elsevier
Dipyridamole (DIP) is a medication utilized to treat cardiovascular diseases, belonging to the
BCS II class of drugs with low solubility and high permeability. As the effectiveness of oral …