The obesity-breast cancer link: a multidisciplinary perspective

EN Devericks, MS Carson, LE McCullough… - Cancer and Metastasis …, 2022 - Springer
Obesity, exceptionally prevalent in the USA, promotes the incidence and progression of
numerous cancer types including breast cancer. Complex, interacting metabolic and …

Relative Dose Intensity of Chemotherapy and Survival in Patients with Advanced Stage Solid Tumor Cancer: A Systematic Review and Meta-Analysis

CM Nielson, LC Bylsma, JP Fryzek, HA Saad… - The …, 2021 - academic.oup.com
Background Chemotherapy-induced toxicities lead to therapy dose reduction or delay,
affecting patient outcomes. This systematic review and meta-analysis evaluated the impact …

Appropriate systemic therapy dosing for obese adult patients with cancer: ASCO guideline update

JJ Griggs, K Bohlke, EP Balaban, JJ Dignam… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE To provide recommendations for appropriate dosing of systemic antineoplastic
agents in obese adults with cancer. METHODS A systematic review of the literature collected …

Low skeletal muscle mass is a predictor of treatment related toxicity in oncologic patients. A meta-analysis

A Surov, M Pech, D Gessner, M Mikusko, T Fischer… - Clinical Nutrition, 2021 - Elsevier
Background & aims The purpose of this meta-analysis was to summarize the published data
regarding associations between occurrence of severe treatment related toxicity and low …

Routine cancer treatments and their impact on physical function, symptoms of cancer-related fatigue, anxiety, and depression

NP Grusdat, A Stäuber, M Tolkmitt, J Schnabel… - Supportive Care in …, 2022 - Springer
Background and purpose Breast cancer can be a major challenge for affected women.
Knowledge of the physical function, symptoms of cancer-related fatigue, anxiety, and …

Sarcopenia and malignancies: epidemiology, clinical classification and implications

FM Zhang, HF Wu, HP Shi, Z Yu, CL Zhuang - Ageing Research Reviews, 2023 - Elsevier
Sarcopenia is a progressive systemic skeletal muscle disorder characterized by a
pathological decline in muscle strength, quantity, and quality, which frequently affects the …

Patient-centric decision framework for treatment alterations in patients with Chemotherapy-induced Peripheral Neuropathy (CIPN)

DL Hertz, DS Childs, SB Park, S Faithfull, Y Ke… - Cancer treatment …, 2021 - Elsevier
Abstract Recently updated American Society of Clinical Oncology (ASCO) guidelines for
Prevention and Management of Chemotherapy-Induced Peripheral Neuropathy (CIPN) in …

Skeletal muscle deconditioning in breast cancer patients undergoing chemotherapy: current knowledge and insights from other cancers

J Mallard, E Hucteau, TJ Hureau… - Frontiers in Cell and …, 2021 - frontiersin.org
Breast cancer represents the most commonly diagnosed cancer while neoadjuvant and
adjuvant chemotherapies are extensively used in order to reduce tumor development and …

The past, present, and future of chemotherapy with a focus on individualization of drug dosing

L DeRidder, DA Rubinson, R Langer… - Journal of Controlled …, 2022 - Elsevier
While there have been rapid advances in developing new and more targeted drugs to treat
cancer, much less progress has been made in individualizing dosing. Even though the …

Obesity and cancer treatment outcomes: interpreting the complex evidence

CGV Slawinski, J Barriuso, H Guo, AG Renehan - Clinical Oncology, 2020 - Elsevier
A wealth of epidemiological evidence, combined with plausible biological mechanisms,
present a convincing argument for a causal relationship between excess adiposity …