Half a century ago, a seminal article on the hitchhiking effect by Smith and Haigh
inaugurated the concept of the selection signature. Selective sweeps are characterised by …

The transition from 'well-marked varieties' of a single species into 'well-defined species'—
especially in the absence of geographic barriers to gene flow (sympatric speciation)—has …

Understanding the impacts of selection pressures influencing modern-day genomic diversity
is a major goal of evolutionary genomics. In particular, the contribution of selective sweeps …

Positive natural selection can lead to a decrease in genomic diversity at the selected site
and at linked sites, producing a characteristic signature of elevated expected haplotype …

Most approaches that capture signatures of selective sweeps in population genomics data
do not identify the specific mutation favored by selection. We present iSAFE (for “integrated …

Human high-altitude (HA) adaptation or mal-adaptation is explored to understand the
physiology, pathophysiology, and molecular mechanisms that underlie long-term exposure …

The identification and classification of selective sweeps are of great significance for
improving the understanding of biological evolution and exploring opportunities for precision …

Premise The degree of gametophyte dependence on the sporophyte life stage is a major
feature that differentiates the life cycles of land plants, yet the evolutionary consequences of …

Resistance to antimalarial drugs, and in particular to the artemisinin derivatives and their
partner drugs, threatens recent progress toward regional malaria elimination and eventual …

The advent of next generation sequencing technologies has made whole-genome and
whole-population sampling possible, even for eukaryotes with large genomes. With this …