Risk factors and early origins of chronic obstructive pulmonary disease
DS Postma, A Bush, M van den Berge - The Lancet, 2015 - thelancet.com
Chronic obstructive pulmonary disease is mainly a smoking-related disorder and affects
millions of people worldwide, with a large effect on individual patients and society as a …
millions of people worldwide, with a large effect on individual patients and society as a …
Human lung development: recent progress and new challenges
MZ Nikolić, D Sun, EL Rawlins - Development, 2018 - journals.biologists.com
Recent studies have revealed biologically significant differences between human and
mouse lung development, and have reported new in vitro systems that allow experimental …
mouse lung development, and have reported new in vitro systems that allow experimental …
A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations
Asthma exacerbations are among the most frequent causes of hospitalization during
childhood, but the underlying mechanisms are poorly understood. We performed a genome …
childhood, but the underlying mechanisms are poorly understood. We performed a genome …
Human embryonic lung epithelial tips are multipotent progenitors that can be expanded in vitro as long-term self-renewing organoids
MZ Nikolić, O Caritg, Q Jeng, JA Johnson, D Sun… - elife, 2017 - elifesciences.org
The embryonic mouse lung is a widely used substitute for human lung development. For
example, attempts to differentiate human pluripotent stem cells to lung epithelium rely on …
example, attempts to differentiate human pluripotent stem cells to lung epithelium rely on …
Early lung development: lifelong effect on respiratory health and disease
J Stocks, A Hislop, S Sonnappa - The lancet Respiratory medicine, 2013 - thelancet.com
Interest in the contribution of changes in lung development during early life to subsequent
respiratory morbidity is increasing. Most evidence of an association between adverse …
respiratory morbidity is increasing. Most evidence of an association between adverse …
Prospective isolation of NKX2-1–expressing human lung progenitors derived from pluripotent stem cells
It has been postulated that during human fetal development, all cells of the lung epithelium
derive from embryonic, endodermal, NK2 homeobox 1–expressing (NKX2-1+) precursor …
derive from embryonic, endodermal, NK2 homeobox 1–expressing (NKX2-1+) precursor …
Single cell RNA analysis identifies cellular heterogeneity and adaptive responses of the lung at birth
The respiratory system undergoes a diversity of structural, biochemical, and functional
changes necessary for adaptation to air breathing at birth. To identify the heterogeneity of …
changes necessary for adaptation to air breathing at birth. To identify the heterogeneity of …
Vitamin D-roles in women's reproductive health?
M Grundmann, F von Versen-Höynck - Reproductive biology and …, 2011 - Springer
In the past few years a growing interest in vitamin D can be observed in the lay and
biomedical literature due to findings demonstrating a low vitamin D status in the population …
biomedical literature due to findings demonstrating a low vitamin D status in the population …
Republished: Lung consequences in adults born prematurely
Although survival has improved significantly in recent years, prematurity remains a major
cause of infant and childhood mortality and morbidity. Preterm births (< 37 weeks of …
cause of infant and childhood mortality and morbidity. Preterm births (< 37 weeks of …
Sex hormone metabolism in lung development and maturation
Sex hormones are increasingly recognized as regulators of lung development. Respiratory
distress syndrome (RDS) is the leading cause of morbidity in preterm neonates and occurs …
distress syndrome (RDS) is the leading cause of morbidity in preterm neonates and occurs …