Background: Cutaneous melanoma is an increasingly common and potentially lethal form of
skin cancer. Current staging systems based on clinical and pathological features have …

ABSTRACT The methyltransferase 14, N6-adenosine-methyltransferase subunit (METTL14)
and Cyclin-dependent kinase inhibitor 2A (CDKN2A) have been identified as involved in the …

Background Melanoma is the most lethal skin cancer, and its incidence has increased
worldwide. About 10% of cases are classified as hereditary melanoma (HM). CDKN2A and …

Cancer is a complex disease that is caused by multiple genetic factors. Researchers have
been studying protein domain mutations to understand how they affect the progression and …

Background/Aim: Melanoma, a variant of skin cancer, presents the highest mortality rates
among all skin cancers. Despite advancements in targeted therapies, immunotherapies, and …

Background/Aim: Genetic variations of the CDKN2A and CDK4 gene have been associated
to melanoma development. In the present study we investigated the potential associations of …

Background Single nucleotide polymorphisms (SNPs) interfere with the function of certain
genes and thus may influence the probability of skin cancer. The correlation between SNPs …

Background: Molecular epidemiology is a novel subject that integrates molecular biology
and basic epidemiology. However, how it is used in specific practical studies, and how it …

Background: The solute carrier family 45-member 2 (SLC45A2) gene, located on
chromosome 5p13. 2, is involved in melanin biosynthesis. Single-nucleotide variants (SNVs) …

Background: Molecular epidemiology is a subject that integrates molecular biology and
basic epidemiology. It introduces biomarkers that are involved in the molecular pathway and …