Cardiac MR: from theory to practice
Cardiovascular disease (CVD) is the leading single cause of morbidity and mortality,
causing over 17. 9 million deaths worldwide per year with associated costs of over $800 …
causing over 17. 9 million deaths worldwide per year with associated costs of over $800 …
Cerebral oxygen extraction fraction MRI: Techniques and applications
The human brain constitutes 2% of the body's total mass but uses 20% of the oxygen. The
rate of the brain's oxygen utilization can be derived from a knowledge of cerebral blood flow …
rate of the brain's oxygen utilization can be derived from a knowledge of cerebral blood flow …
Diminished cerebral oxygen extraction and metabolic rate in sickle cell disease using T2 relaxation under spin tagging MRI
Purpose T2 MRI oximetry can noninvasively determine oxygen saturation (Y) but requires
empirical MR calibration models to convert the measured blood transverse relaxation (T2b) …
empirical MR calibration models to convert the measured blood transverse relaxation (T2b) …
Quantitative theory for the transverse relaxation time of blood water
W Li, PCM van Zijl - NMR in Biomedicine, 2020 - Wiley Online Library
An integrative model is proposed to describe the dependence of the transverse relaxation
rate of blood water protons (R2blood= 1/T2blood) on hematocrit fraction and oxygenation …
rate of blood water protons (R2blood= 1/T2blood) on hematocrit fraction and oxygenation …
Validation of T2‐based oxygen extraction fraction measurement with 15O positron emission tomography
Purpose To evaluate the accuracy of T2‐based whole‐brain oxygen extraction fraction
(OEF) estimation by comparing it with gold standard 15O‐PET measurements. Methods …
(OEF) estimation by comparing it with gold standard 15O‐PET measurements. Methods …
Cerebral hemodynamics and executive function in sickle cell anemia
Background and Purpose: Individuals with sickle cell anemia experience cognitive deficits,
even in the absence of cerebral infarcts or strokes. This study tested the hypothesis that …
even in the absence of cerebral infarcts or strokes. This study tested the hypothesis that …
Reduced global cerebral oxygen metabolic rate in sickle cell disease and chronic anemias
Anemia is the most common blood disorder in the world. In patients with chronic anemia,
such as sickle cell disease or major thalassemia, cerebral blood flow increases to …
such as sickle cell disease or major thalassemia, cerebral blood flow increases to …
Cerebral oxygen metabolism in adults with sickle cell disease
In sickle cell disease (SCD), oxygen delivery is impaired due to anemia, especially during
times of increased metabolic demand, and cerebral blood flow (CBF) must increase to meet …
times of increased metabolic demand, and cerebral blood flow (CBF) must increase to meet …
Quantification of whole‐brain oxygenation extraction fraction and cerebral metabolic rate of oxygen consumption in adults with sickle cell anemia using individual T2 …
Purpose To evaluate different T2‐oxygenation calibrations for estimating venous
oxygenation in people with sickle cell anemia (SCA). Methods Blood T2 values were …
oxygenation in people with sickle cell anemia (SCA). Methods Blood T2 values were …
Reduced oxygen extraction efficiency in sickle cell anemia patients with evidence of cerebral capillary shunting
MR Juttukonda, MJ Donahue… - Journal of Cerebral …, 2021 - journals.sagepub.com
Arterial spin labeling (ASL) magnetic resonance imaging (MRI) utilizes arterial blood water
as an endogenous contrast agent to provide a quantitative measure of cerebral blood flow …
as an endogenous contrast agent to provide a quantitative measure of cerebral blood flow …