Vincristine, a vinca alkaloid, is used in chemotherapy protocols for cancers such as acute
leukemia, Hodgkin's disease, neuroblastoma, cervical carcinoma, lymphomas, breast …

Aim The main aim of the study was to evaluate the inflammatory response and development
of apical periodontitis in rats chronically treated with glucocorticoids. Methodology Male …

The present study was designed to investigate the role of mast cells and mast cell-derived
histamine in vincristine-induced neuropathic pain. Neuropathic pain was induced by …

Background. Osteoporosis is one of the most common yet difficult to treat diseases. It affects
millions of people and costs the health care systems billions worldwide. All of the available …

Glucocorticoids (GCs) are frequently used for the suppression of inflammation in chronic
inflammatory diseases. Excessive GCs usage is greatly associated with several side effects …

Background: Periodontitis preceded by gingivitis is the most common form of periodontal
disease and occurs due to the interaction of microorganisms present in the complex …

Mast cells are multifunctional immune cells that participate in many important processes
such as defense against pathogens, allergic reactions, and tissue repair. These cells …

Background Histamine regulates function of osteoclasts and osteoblasts, however data
regarding the influence of histamine H2 receptors antagonists on bone tissue are …

Objective: Glucocorticoids induced osteoporosis and its related fragility fractures represent a
costly human and socioeconomic load worldwide. All the current pharmacological therapies …

Background: Osteoporosis is a systemic skeletal disorder that increases bone fragility and
risk of fractures. Current medications for treating osteoporosis are associated with …