Background Multiple sclerosis (MS) is a chronic and autoimmune disease of the central
nervous system (CNS), mainly characterized by inflammatory demyelination, which …

Multiple sclerosis (MS) as a chronic inflammatory disorder of the central nervous system
(CNS) is thought to be caused by the abnormal induction of immune responses …

Background In myelin oligodendrocyte glycoprotein (MOG)-induced experimental
autoimmune encephalomyelitis (EAE), several areas of demyelination are detectable in …

MicroRNAs (miRNAs) are small RNA molecules with regulatory functions on the expression
of genes through binding directly to target messenger RNA (mRNA) transcripts, eventuating …

Background Interleukin 23 is a critical cytokine in the pathogenesis of multiple sclerosis. But
the local impact of interleukin 23 on the course of neuroinflammation is still not well defined …

Background Previous studies have reported the occurrence of psoriasis together with
multiple sclerosis (MS). Although similar predisposing genes and pathomechanisms have …

Background Several studies have reported the association between polymorphisms in
Matrix metalloproteinases (MMPs) gene family and risk of Multiple sclerosis (MS). However …

Although IL-23 and downstream signal transduction play essential roles in
neuroinflammation, the local impact of IL-23 in multiple sclerosis is still not fully understood …

Alzheimer's Disease (AD) is the most common form of dementia, characterised by
extracellular amyloid deposition as plaques and intracellular neurofibrillary tangles of tau …

In 1989 ILAR published a list and description of immunodeficient rodents used in research.
Since then, advances in understanding of molecular mechanisms; recognition of genetic …