Molecular characterization of upper tract urothelial carcinoma in the era of next-generation sequencing: a systematic review of the current literature

MR Hassler, F Bray, JWF Catto, AP Grollman… - European urology, 2020 - Elsevier
Context While upper tract urothelial carcinoma (UTUC) share histological appearance with
bladder cancer (BC), the former has differences in etiology and clinical phenotype consistent …

Genetic differences between bladder and upper urinary tract carcinoma: implications for therapy

JP Sfakianos, Z Gul, SF Shariat, SF Matin… - European urology …, 2021 - Elsevier
Context Bladder urothelial carcinoma (BUC) and upper tract urothelial carcinoma (UTUC)
have genetic differences, which may influence therapy. Objective The aim of the current …

Compression-induced dedifferentiation of adipocytes promotes tumor progression

Y Li, AS Mao, BR Seo, X Zhao, SK Gupta, M Chen… - Science …, 2020 - science.org
Dysregulated physical stresses are generated during tumorigenesis that affect the
surrounding compliant tissues including adipocytes. However, the effect of physical …

miR-665 inhibits epithelial-to-mesenchymal transition in bladder cancer via the SMAD3/SNAIL axis

W Wang, Y Ying, H Xie, J Li, X Ma, L He, M Xu, S Chen… - Cell Cycle, 2021 - Taylor & Francis
Emerging research indicates that miRNAs can regulate cancer progression by influencing
molecular pathways. Here, we studied miR-665, part of the DLK1-DIO3 miRNA cluster …

[HTML][HTML] Plasma proteomic profiling discovers molecular features associated with upper tract urothelial carcinoma

Y Qu, Z Yao, N Xu, G Shi, J Su, S Ye, K Chang, K Li… - Cell Reports …, 2023 - cell.com
Upper tract urothelial carcinoma (UTUC) is often diagnosed late and exhibits poor
prognosis. Limited data are available on potential non-invasive biomarkers for disease …

MET/SMAD3/SNAIL circuit mediated by miR-323a-3p is involved in regulating epithelial–mesenchymal transition progression in bladder cancer

J Li, X Xu, S Meng, Z Liang, X Wang, M Xu… - Cell death & …, 2017 - nature.com
Bladder cancer (BCa) is the one of the most common cancers with high incidence,
occurrence and low 5-year survival rate. Emerging evidence indicates that DLK1-DIO3 …

Long noncoding RNA LINC02470 sponges MicroRNA-143-3p and enhances SMAD3-mediated epithelial-to-mesenchymal transition to promote the aggressive …

CS Huang, CH Tsai, CP Yu, YS Wu, MF Yee, JY Ho… - Cancers, 2022 - mdpi.com
Simple Summary Long noncoding RNAs (lncRNAs) were proposed as novel tumor
prognostic markers, including for predicting bladder cancer progression, and the competing …

A novel risk signature for predicting brain metastasis in patients with lung adenocarcinoma

Y Zhao, S Gu, L Li, R Zhao, S Xie, J Zhang… - Neuro …, 2023 - academic.oup.com
Background Brain metastasis (BM) are a devastating consequence of lung cancer. This
study was aimed to screen risk factors for predicting BM. Methods Using an in vivo BM …

Novel gene signatures predictive of patient recurrence-free survival and castration resistance in prostate cancer

B Zhang, Z Zhang, H Hu, JT Dong - Cancers, 2021 - mdpi.com
Simple Summary Molecular signatures predictive of recurrence-free survival (RFS) and
castration resistance are critical for treatment decision-making in prostate cancer (PCa), but …

[HTML][HTML] Molecular characterization of urothelial carcinoma of the bladder and upper urinary tract

JY Lee, K Kim, HH Sung, HG Jeon, BC Jeong… - Translational …, 2018 - Elsevier
PURPOSE: A better understanding of the molecular basis of urothelial carcinoma (UC) is
needed to refine the clinical decision-making process. METHODS AND MATERIALS: We …