[PDF][PDF] Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the …
OP-EHEA191011_online 2313..2340 Page 1 Low-density lipoproteins cause atherosclerotic
cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus …
cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus …
Polycyclic aromatic hydrocarbon and its effects on human health: An overeview
Polycyclic aromatic hydrocarbons (PAHs) are a class of chemicals of considerable
environmental significance. PAHs are chemical contaminants of fused carbon and hydrogen …
environmental significance. PAHs are chemical contaminants of fused carbon and hydrogen …
Genome-wide meta-analysis of insomnia prioritizes genes associated with metabolic and psychiatric pathways
Insomnia is a heritable, highly prevalent sleep disorder for which no sufficient treatment
currently exists. Previous genome-wide association studies with up to 1.3 million subjects …
currently exists. Previous genome-wide association studies with up to 1.3 million subjects …
[HTML][HTML] Associations between blood type and COVID-19 infection, intubation, and death
The rapid global spread of the novel coronavirus SARS-CoV-2 has strained healthcare and
testing resources, making the identification and prioritization of individuals most at-risk a …
testing resources, making the identification and prioritization of individuals most at-risk a …
Systems biology in cardiovascular disease: a multiomics approach
Omics techniques generate large, multidimensional data that are amenable to analysis by
new informatics approaches alongside conventional statistical methods. Systems theories …
new informatics approaches alongside conventional statistical methods. Systems theories …
Comprehensive functional genomic resource and integrative model for the human brain
INTRODUCTION Strong genetic associations have been found for a number of psychiatric
disorders. However, understanding the underlying molecular mechanisms remains …
disorders. However, understanding the underlying molecular mechanisms remains …
Identification of 64 novel genetic loci provides an expanded view on the genetic architecture of coronary artery disease
P Van Der Harst, N Verweij - Circulation research, 2018 - Am Heart Assoc
Rationale: Coronary artery disease (CAD) is a complex phenotype driven by genetic and
environmental factors. Ninety-seven genetic risk loci have been identified to date, but the …
environmental factors. Ninety-seven genetic risk loci have been identified to date, but the …
Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis
In response to various stimuli, vascular smooth muscle cells (SMCs) can de-differentiate,
proliferate and migrate in a process known as phenotypic modulation. However, the …
proliferate and migrate in a process known as phenotypic modulation. However, the …
[HTML][HTML] Interpreting findings from Mendelian randomization using the MR-Egger method
S Burgess, SG Thompson - European journal of epidemiology, 2017 - Springer
Abstract Mendelian randomization-Egger (MR-Egger) is an analysis method for Mendelian
randomization using summarized genetic data. MR-Egger consists of three parts:(1) a test …
randomization using summarized genetic data. MR-Egger consists of three parts:(1) a test …
Discovery of common and rare genetic risk variants for colorectal cancer
To further dissect the genetic architecture of colorectal cancer (CRC), we performed whole-
genome sequencing of 1,439 cases and 720 controls, imputed discovered sequence …
genome sequencing of 1,439 cases and 720 controls, imputed discovered sequence …