Anthracycline Cardiotoxicity in Adult Cancer Patients: JACC: CardioOncology State-of-the-Art Review

M Camilli, CM Cipolla, S Dent, G Minotti, DM Cardinale - Cardio Oncology, 2024 - jacc.org
Since their introduction in the 1960s, anthracyclines have been a significant breakthrough in
oncology, introducing dramatic changes in the treatment of solid and hematologic …

[HTML][HTML] Research progress on the mechanism, monitoring, and prevention of cardiac injury caused by antineoplastic drugs—anthracyclines

Y Chen, W Yang, X Cui, H Zhang, L Li, J Fu, H Guo - Biology, 2024 - mdpi.com
Simple Summary Anthracycline drugs, as a class of commonly used antitumor
chemotherapeutics, play a significant role in the treatment of various cancers. However, they …

Cardiovascular Toxicity in Cancer Therapy: Protecting the Heart while Combating Cancer

A Manhas, D Tripathi, D Thomas, N Sayed - Current cardiology reports, 2024 - Springer
Abstract Purpose of Review This review explores the cardiovascular toxicity associated with
cancer therapies, emphasizing the significance of the growing field of cardio-oncology. It …

Genetic and epigenetic bases of long-term adverse effects of childhood cancer therapy

Z Wang, J Zhang - Nature Reviews Cancer, 2024 - nature.com
Over the past decade, genome-scale molecular profiling of large childhood cancer
survivorship cohorts has led to unprecedented advances in our understanding of the genetic …

[HTML][HTML] Evolving therapeutics and ensuing cardiotoxicities in triple-negative breast cancer

C Wang, P Fan, Q Wang - Cancer Treatment Reviews, 2024 - Elsevier
Defined as scarce expression of hormone receptors and human epidermal growth factor
receptor 2, triple-negative breast cancer (TNBC) is labeled as the most heterogeneous …

Genetic factors in the pathogenesis of cardio-oncology

Y Qi, Y Wei, L Li, H Ge, Y Wang, C Zeng… - Journal of Translational …, 2024 - Springer
In recent years, with advancements in medicine, the survival period of patients with tumours
has significantly increased. The adverse effects of tumour treatment on patients, especially …

Straight to the heart: Protecting the patient's heart during chemotherapy

R Conyers, DA Elliott - Cell Stem Cell, 2024 - cell.com
How do we protect the heart during chemotherapy with the anthracycline drug class?
Tackling this question, Liu et al. combined pluripotent stem cell models, CRISPR genetic …

[HTML][HTML] Harnessing iPSCs to Dissect Causality in Anthracycline-Induced Cardiotoxicity: All That Fits Are Not Hits

D Thomas, A Manhas, N Sayed - Cardio Oncology, 2024 - jacc.org
Anthracyclines can result in cardiotoxic effects, which can occur acutely and chronically.
Patients with breast cancer, lymphoma, sarcoma, and leukemia are still treated with …

Étude de la survenue de maladies cardiaques à long terme après le traitement du cancer dans l'enfance: Identification de marqueurs biologiques associés

N Aba - 2024 - theses.hal.science
Les progrès en oncologie pédiatrique ont conduit à améliorer le pronostic des patients
traités pour un cancer de l'enfant ou de l'adolescent avec une survie à 5 ans supérieure à …