[HTML][HTML] Articular cartilage and osteochondral tissue engineering techniques: Recent advances and challenges

W Wei, H Dai - Bioactive materials, 2021 - Elsevier
In spite of the considerable achievements in the field of regenerative medicine in the past
several decades, osteochondral defect regeneration remains a challenging issue among …

Bioinspired gradient scaffolds for osteochondral tissue engineering

Y Peng, Y Zhuang, Y Liu, H Le, D Li, M Zhang… - …, 2023 - Wiley Online Library
Repairing articular osteochondral defects present considerable challenges in self‐repair
due to the complex tissue structure and low proliferation of chondrocytes. Conventional …

Use of nanoparticles in tissue engineering and regenerative medicine

M Fathi-Achachelouei, H Knopf-Marques… - … in bioengineering and …, 2019 - frontiersin.org
Advances in nanoparticle (NP) production and demand for control over nanoscale systems
have had significant impact on tissue engineering and regenerative medicine (TERM). NPs …

3D bioprinting for cartilage and osteochondral tissue engineering

AC Daly, FE Freeman… - Advanced …, 2017 - Wiley Online Library
Significant progress has been made in the field of cartilage and bone tissue engineering
over the last two decades. As a result, there is real promise that strategies to regenerate …

[HTML][HTML] Hydrogel as a bioactive material to regulate stem cell fate

YH Tsou, J Khoneisser, PC Huang, X Xu - Bioactive materials, 2016 - Elsevier
The encapsulation of stem cells in a hydrogel substrate provides a promising future in
biomedical applications. However, communications between hydrogels and stem cells is …

Nonadhesive alginate hydrogels support growth of pluripotent stem cell-derived intestinal organoids

MM Capeling, M Czerwinski, S Huang, YH Tsai, A Wu… - Stem cell reports, 2019 - cell.com
Human intestinal organoids (HIOs) represent a powerful system to study human
development and are promising candidates for clinical translation as drug-screening tools or …

Combinatorial hydrogels with biochemical gradients for screening 3D cellular microenvironments

SL Vega, MY Kwon, KH Song, C Wang… - Nature …, 2018 - nature.com
Abstract 3D microenvironmental parameters control cell behavior, but can be challenging to
investigate over a wide range of conditions. Here, a combinatorial hydrogel platform is …

3D printed cartilage‐like tissue constructs with spatially controlled mechanical properties

BAG de Melo, YA Jodat, S Mehrotra… - Advanced functional …, 2019 - Wiley Online Library
Developing biomimetic cartilaginous tissues that support locomotion while maintaining
chondrogenic behavior is a major challenge in the tissue engineering field. Specifically …

[HTML][HTML] 4D biofabrication via instantly generated graded hydrogel scaffolds

A Ding, SJ Lee, S Ayyagari, R Tang, CT Huynh… - Bioactive materials, 2022 - Elsevier
Formation of graded biomaterials to render shape-morphing scaffolds for 4D biofabrication
holds great promise in fabrication of complex structures and the recapitulation of critical …

Bioactive factor delivery strategies from engineered polymer hydrogels for therapeutic medicine

MK Nguyen, E Alsberg - Progress in polymer science, 2014 - Elsevier
Polymer hydrogels have been widely explored as therapeutic delivery matrices because of
their ability to present sustained, localized and controlled release of bioactive factors …