Molecular basis of human noradrenaline transporter reuptake and inhibition

J Tan, Y Xiao, F Kong, X Zhang, H Xu, A Zhu, Y Liu… - Nature, 2024 - nature.com
Noradrenaline, also known as norepinephrine, has a wide range of activities and effects on
most brain cell types. Its reuptake from the synaptic cleft heavily relies on the noradrenaline …

Structure of the human dopamine transporter in complex with cocaine

JC Nielsen, K Salomon, IE Kalenderoglou… - Nature, 2024 - nature.com
The dopamine transporter (DAT) is crucial for regulating dopamine signalling and is the
prime mediator for the rewarding and addictive effects of cocaine. As part of the …