Hydrogels have been widely investigated in biomedical fields due to their similar physical
and biochemical properties to the extracellular matrix (ECM). Collagen and hyaluronic acid …

Microbial bioproduction of chemicals, proteins, and primary metabolites from cheap carbon
sources is currently an advancing area in industrial research. The model yeast …

Since it is known that hyaluronic acid contributes to soft tissue growth, elasticity, and scar
reduction, different strategies of producing HA have been explored in order to satisfy the …

Microbial production of hyaluronic acid (HA) is an area of research that has been gaining
attention in recent years due to the increasing demand for this biopolymer for several …

The introduction of unnatural chemical moieties into glycosaminoglycans (GAGs) has
enormous potential to facilitate studies of the mechanism and application of these critical …

As the two most widely used Kluyveromyces yeast, Kluyveromyces marxianus and K. lactis
have gained increasing attention as microbial chassis in biocatalysts, biomanufacturing and …

Compared with chemical synthesis and tissue extraction methods, microbial synthesis of
glycosaminoglycans (GAGs) is attractive because of the advantages of eco-friendly …

Highlights•Scenario evaluation and in silico tools streamline host selection and
construction.•Advances in filamentous fungi have expanded the scope of non-model host …

Hyaluronic acid (HA) is a polysaccharide of alternating d-glucuronic acid and N-acetyl-d-
glucosamine residues present in the extracellular matrix of connective, epithelial, and …

The unique biological and rheological properties make hyaluronic acid a sought-after
material for medicine and cosmetology. Due to very high purity requirements for hyaluronic …