Leukaemia: a model metastatic disease

AE Whiteley, TT Price, G Cantelli, DA Sipkins - Nature Reviews Cancer, 2021 - nature.com
In contrast to solid cancers, which often require genetic modifications and complex cellular
reprogramming for effective metastatic dissemination, leukaemic cells uniquely possess the …

Novel insights into the function of CD24: A driving force in cancer

P Altevogt, M Sammar, L Hüser… - International journal of …, 2021 - Wiley Online Library
CD24 is a highly glycosylated protein with a small protein core that is linked to the plasma
membrane via a glycosyl‐phosphatidylinositol anchor. CD24 is primarily expressed by …

CD24: a novel target for cancer immunotherapy

E Panagiotou, NK Syrigos, A Charpidou… - Journal of Personalized …, 2022 - mdpi.com
Cluster of differentiation 24 (CD24) is a small, highly glycosylated cell adhesion protein that
is normally expressed by immune as well as epithelial, neural, and muscle cells. Tumor …

Dormant breast cancer micrometastases reside in specific bone marrow niches that regulate their transit to and from bone

TT Price, ML Burness, A Sivan, MJ Warner… - Science translational …, 2016 - science.org
Breast cancer metastatic relapse can occur years after therapy, indicating that disseminated
breast cancer cells (BCCs) have a prolonged dormant phase before becoming proliferative …

The impact of matrix metalloproteinase-9 on the sequential steps of the metastatic process

G Barillari - International journal of molecular sciences, 2020 - mdpi.com
In industrialized countries, cancer is the second leading cause of death after cardiovascular
disease. Most cancer patients die because of metastases, which consist of the self …

[HTML][HTML] Dendrimer-mediated multivalent binding for enhanced capture of tumor cells

JH Myung, KA Gajjar, J Saric… - … (International ed. in …, 2011 - ncbi.nlm.nih.gov
Multivalent binding, the simultaneous binding of multiple ligands to multiple receptors, has
played a central role in a number of pathological processes, including the attachment of …

CD24 is a potential immunotherapeutic target for mantle cell lymphoma

JÁ Freile, N Ustyanovska Avtenyuk, MG Corrales… - Biomedicines, 2022 - mdpi.com
CD24 and its ligand Siglec-10 were described as an innate immune checkpoint in
carcinoma. Here, we investigated this axis in B-cell lymphoma by assessing CD24 …

Prospects of antibodies targeting CD47 or CD24 in the treatment of glioblastoma

H Wu, J Liu, Z Wang, W Yuan… - CNS neuroscience & …, 2021 - Wiley Online Library
Glioma is a malignant tumor with the highest incidence among all brain tumors (about 46%
of intracranial tumors) and is the most common primary intracranial tumor. Among them …

The potential role of HIF on tumour progression and dissemination

S Unwith, H Zhao, L Hennah… - International journal of …, 2015 - Wiley Online Library
Cancer is the second cause of mortality worldwide, primarily owing to failure to cure
metastatic disease. The need to target the metastatic process to reduce mortality is clear and …

Brain metastasization of breast cancer

T Custodio-Santos, M Videira, MA Brito - Biochimica et Biophysica Acta …, 2017 - Elsevier
Central nervous system metastases have been reported in 15–25% of breast cancer
patients, and the incidence is increasing. Moreover, the survival of these patients is …