[HTML][HTML] Brugada syndrome: A comprehensive review of pathophysiological mechanisms and risk stratification strategies

KHC Li, S Lee, C Yin, T Liu, T Ngarmukos, G Conte… - IJC Heart & …, 2020 - Elsevier
Brugada syndrome (BrS) is an inherited ion channel channelopathy predisposing to
ventricular arrhythmias and sudden cardiac death. Originally believed to be predominantly …

Tpeak‐Tend, Tpeak‐Tend/QT ratio and Tpeak‐Tend dispersion for risk stratification in Brugada Syndrome: A systematic review and meta‐analysis

G Tse, M Gong, CKH Li, KSK Leung… - Journal of …, 2018 - Wiley Online Library
Background Brugada syndrome is an ion channelopathy that predisposes affected subjects
to ventricular tachycardia/fibrillation (VT/VF), potentially leading to sudden cardiac death …

Catheter ablation as an adjunctive therapy to ICD implantation in Brugada syndrome

I Doundoulakis, S Chiotis, L Pannone… - … Journal-Quality of …, 2024 - academic.oup.com
Abstract Background Brugada Syndrome (BrS) is a life-threatening cardiac arrhythmia
disorder associated with an increased risk of ventricular arrhythmias (VAs) and sudden …

dST-Tiso interval, a novel electrocardiographic marker of ventricular arrhythmia inducibility in individuals with ajmaline-induced Brugada type I pattern

S Iacopino, GB Chierchia, P Sorrenti, F Pesce… - The American Journal of …, 2021 - Elsevier
The aim of this study was to investigate the reliability of a novel electrocardiographic (ECG)
marker in predicting ventricular arrhythmia (VA) inducibility in individuals with drug-induced …

Higher dispersion measures of conduction and repolarization in type 1 compared to non-type 1 Brugada syndrome patients: an electrocardiographic study from a …

G Tse, KHC Li, G Li, T Liu, G Bazoukis… - Frontiers in …, 2018 - frontiersin.org
Background: Brugada syndrome (BrS) is a cardiac ion channelopathy that predisposes
affected individuals to sudden cardiac death (SCD). Type 1 BrS is thought to take a more …

[HTML][HTML] High risk electrocardiographic markers in Brugada syndrome

D Asvestas, G Tse, A Baranchuk, G Bazoukis, T Liu… - IJC heart & …, 2018 - Elsevier
Several clinical, electrocardiographic (ECG) and electrophysiological markers have been
proposed to provide optimal risk stratification in patients with Brugada syndrome (BrS). Of …

Historical perspective and recent progress in cardiac ion channelopathies research and clinical practice in Hong Kong

KSK Leung, H Huang, CT Chung, D Radford… - International Journal of …, 2023 - Springer
Cardiac ion channelopathies encompass a set of inherited or acquired conditions that are
due to dysfunction in ion channels or their associated proteins, typically in the presence of …

Association between lipoprotein (a) and premature atherosclerotic cardiovascular disease: a systematic review and meta-analysis

X Tian, N Zhang, G Tse, G Li, Y Sun… - European Heart Journal …, 2024 - academic.oup.com
Abstract Background and aims High Lipoprotein (a)[Lp (a)] level has been demonstrated as
an important risk factor for atherosclerotic cardiovascular diseases (ASCVD) amongst the …

[HTML][HTML] Spontaneous type 1 ECG and arrhythmic risk in Brugada syndrome: A meta-analysis of adjusted time-to-event data

S Chiotis, L Pannone, I Doundoulakis, DG Della Rocca… - Heart Rhythm O2, 2024 - Elsevier
Background Brugada syndrome (BrS) is associated with an increased risk of major
arrhythmic events (MAEs), particularly in patients with a spontaneous type 1 …

Electrocardiographic evidence of abnormal atrial phenotype in Brugada syndrome

G Tse, S Reddy, J Chopra, S Lee, T Liu… - Journal of …, 2019 - Elsevier
Abstract Background Brugada syndrome (BrS) is an inherited ion channelopathy that may
predispose affected individuals to atrial cardiomyopathy. We tested the hypothesis that BrS …